Groselle led the way for Creighton (8-4) with 27 points. The 7-foot senior was 8 of 9 from the field and 11 of 14 from the foul line to surpass a previous best of 20 points he registered in a 97-76 win against UMass on Nov. 25.
Maurice Watson Jr. added 16 points, Harrell had 14 points, 11 rebounds and five assists and Hanson had 13 points.
The Bluejays opened the game with a 19-7 run and led 54-39 at the break. North Texas (4-8) never threatened in the second half.