The teams met for the first time since the 1994-95 season. The Rams are 5-0 against Buffalo and 14-7 all-time against teams from the Mid-American Conference.
VCU (6-5) built a 40-27 advantage by halftime and outscored the Bulls by eight in the second half, 50-42.
Johnson was 7 of 11 from the field, 3 of 3 from the free-throw line and collected three steals.
VCU was 34-of-69 (49.3 percent) shooting from the field, including 9 of 26 from distance, while making 18 steals and forcing Buffalo into 31 turnovers.