The NAIA Hornets were led by Jalen Fletcher, who made 14 of 20 shots for 30 points. Evan Jones added 13 points.
The Hornets led 20-4 after the Redhawks missed six of their first eight shots and turned the ball over five times before responding with a 27-8 run during which the Hornets had 11 turnovers. The Hornets took the lead a final time before Southeast Missouri finished the half on a 9-3 spurt.
A 3-pointer by Calvin gave the Redhawks a double-digit lead for good with 14:55 left in the game. The lead reached 20 on a Jones 3-pointer with 3:43 remaining.