Andrien White and Curran Scott, both freshmen, had breakout nights with 20 points apiece for the 49ers (3-9). Scott had scored 19 points in the previous four games combined and White reached double digits for the first time in the last six games.
Charlotte's 111 points was its largest total in more than a year, and the 49ers shot 60 percent (42-70).
The teams traded scoring runs in the first half before Uchebo took over in the second, scoring eight straight points as the 49ers stretched a four-point lead to 10, 59-49, in the first two-and-a-half minutes.
Jon Davis added 17 points and seven assists for Charlotte.