The Panthers shot 31 of 50 (62 percent) from the field, including 10 of 16 from beyond distance, and collected 25 assists on 31 made baskets.
Brown hit a pair of field goals during a 10-0 run that spanned halftime and put High Point up 51-35. The Panthers maintained a double-digit lead they pushed to as many as 20 points, 82-62 with under two minutes to play.
High Point (12-4, 5-0) built a 46-35 lead in the first half and cruised to the win.
The Panthers have won five straight over the Blue Hose and lead the overall series, 13-8.