The Chanticleers (10-8, 4-4 Big South), who never trailed, stretched an eight-point halftime lead to 54-42 with 10 minutes remaining.
High Point (12-6, 5-2) used a 24-15 run to pull to 69-66 with 15 seconds left. John Brown scored nine of his 18 points, and Anthony Lindauer made a 3-pointer to cap the Panthers' surge. Brown forced a turnover on the ensuing inbounds, and Adam Weary was fouled on a tip-in attempt and made two free throws to make it 69-68.
Shivaughn Wiggins added two free throws to stretch the Chanticleers' lead to 71-68 with 12.4 seconds remaining.
Lorenzo Cugini's missed 3-point attempt was knocked out of bounds by Coastal Carolina with 2.4 left. Cugini's second potentially game-tying 3 hit the back of the rim to end it.