Aryon Hutton knocked down a 3-pointer to pull Quinnipiac, which trailed 51-40 with 8:15 remaining, within 54-53 with 2:32 to play. From there, the Bobcats missed their last six shots and had a turnover.
Kassius Robertson added 11 points for Canisius, which came averaging 81.2 points while the Bobcats allowed 72.3. The Golden Griffins made 13 of 27 shots in the second half.
Hutton led Quinnipiac (5-11, 2-5) with 15 points and Daniel Harris had 14. The Bobcats shot just 34.5 percent (19 of 55) and had 16 turnovers that Canisius turned in 21 points.