Houston led by eight points with three minutes left in regulation before East Carolina closed on a 9-1 run. The Cougars' Devonta Pollard missed the front end of a 1-and-1 with 35.3 seconds left and ECU's Caleb White sank a 3-pointer from the wing to tie it at 75-all. Houston played for the final shot but turned it over.
VanBeck scored seven of Houston's first nine points of the second overtime for a 93-91 lead. He added a free throw with three seconds left for a two-possession game.
Dotson added 23 points and 13 rebounds for Houston (15-6, 5-4 American).
B.J. Tyson scored 20 points for East Carolina (10-12, 2-7).