Gahafer finished 30 of 43 for 277 yards, and the Eagles (1-1) avenged last year's 13-10 loss to NAIA Pikeville (1-1). Gahafer's fifth touchdown pass gave Morehead State a 42-10 lead early in the third quarter.
The Bears answered with three straight touchdowns, cutting the deficit to 42-29 on Sani Warren's 24-yard touchdown pass with 4:08 left in the game.
Brandon Bornhauser returned the ensuing onside kickoff 45 yards for a Morehead State touchdown to seal the win.
Seth Millar led Pikeville with 15 carries for 130 yards and four touchdowns. His fourth scoring run pulled the Bears within 49-36 with 56 seconds to play.