October 06, 2014
Florida State's Rashad Greene makes a leaping reception despite the defensive effort of Wake Forest's Ryan Janvion during the first quarter of an NCAA college football game, Saturday Oct. 4, 2014 in Tallahassee, Fla. (AP Photo/Steve Cannon)
Steve Cannon

TALLAHASSEE, Fla. (AP) Top-ranked Florida State could be missing three starters when the Seminoles play at Syracuse on Saturday.

Coach Jimbo Fisher announced Monday center Austin Barron is out with an arm injury and will be replaced by redshirt freshman Ryan Hoefeld. Leading receiver Rashad Greene suffered a concussion in last weekend's 43-3 win against Wake Forest and has not been cleared to return. Running back Karlos Williams injured his ankle during the game and is in a walking boot.

Redshirt sophomore Mario Pender would replace Williams if he is unable to play and freshman Dalvin Cook would be the primary backup. Pender and Cook have run for a combined 382 yards and five touchdowns.

''If I had to give a percentage, I would say yes'' Williams will miss the game, Fisher said. ''But it's how guys heal and where they're at.''

Sophomore Jesus ''Bobo'' Wilson could start in place of Greene, but freshman Travis Rudolph is also a candidate. Greene is four receptions from setting the school record for career catches.

The Seminoles could also be a play away from an emergency situation at quarterback. Backup Sean Maguire is out after injuring his hand against Wake Forest. Fisher said Jameis Winston's backup would either be redshirt freshman John Franklin or walk-on redshirt freshman Troy Cook.

Neither has ever thrown a collegiate pass and Franklin has spent much of the season working as a receiver.

The Seminoles have had a variety of short-term ailments keep players out of games this season after being relatively-injury free during the title run.

Starting defensive end and Pender both missed the N.C. State game with concussions. Nose tackle Niles Lawrence-Stample is out for the season with a torn pectoral muscle. His replacement, Derrick Mitchell, Jr., missed last week with a knee problem and cornerback P.J. Williams has missed a game with a hamstring issue.

''You're always concerned, but ... they're not pulls and tears,'' Fisher said. ''When you run a bunch of big guys into each other, things break sometimes.

''That's just ball. You get a bunch of bodies falling around out there, that happens. ... Sometimes the gods smile on you, sometimes they don't. That doesn't mean you still can't have success. You've got to have a plan.''

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