Coming into the game averaging 76.6 rushing yards per game, Stanton gained 180 yards on 24 carries and gave Harvard a 7-0 lead after a 3-yard run.
Smith hit fellow wide receiver Firkser on a 37-yard scoring pass, Stanton added another score on a 2-yard run and Harvard (7-0, 4-0 Ivy League Conference) led 20-9 at half time.
Dartmouth (5-2, 3-1) scored on a 2-yard TD run by Kyle Bramble, but Alex Gakenheimer's point-after try was blocked. Gakenheimer kicked field goals of 30 and 22 yards. Dalyn Williams was 16 of 26 for 210 yards passing for the Big Green.
Andrew Flesher kicked a 33-yard field goal for Harvard.
The game marked the 118th meeting between the teams in a rivalry dating to 1882.