Noel broke a 21-all tie in the fourth quarter with a 63-yard strike to Moses Webb. CCSU responded with a 54-yard touchdown run by Brenden Lytton. A missed extra point kept the Pioneers (8-2, 4-1 Northeast) ahead 28-27.
Noel answered back with a 12-play, 64-yard drive capped by his 18-yard score to Tyler Dube with 7:47 left.
The Blue Devils (2-8, 0-5) had three more chances to tie it, but Nick SanGiacomo threw two interceptions in the final minutes.
Lytton paced the Blue Devils with 193 yards on 30 carries and a pair of scores.