Catalon has been ruled out for Saturday night after not practicing all week.
While TCU officials didn't elaborate on his injury, Catalon took a hard shot to his upper body a week earlier at West Virginia. That came on a 2-yard run with 4 seconds left, the last play before Jaden Oberkrom kicked a 37-yard field goal to give TCU a 31-30 victory.
Catalon has 493 yards rushing and 10 TDs for the Horned Frogs. He has 14 catches for 163 yards and a score.
TCU is sixth in the College Football Playoff rankings, one spot ahead of Kansas State.