Melville was sacked, but then converted the third-and-long with a 28-yard pass to Alex Greenawalt. Wilkins plunged in from 3 yards out for the final margin.
Trey Lauletta couldn't rally the Bison (8-3, 4-2), throwing two of his three interceptions in the final quarter.
Melville threw for 140 yards on 9-of-21 passing. Wilkins had 51 yards on 12 carries.
Lauletta threw for 229 yards and Will Carter had 81 yards receiving.