Buoyed by a comeback win on the road against a ranked team, Oklahoma will try to keep rolling when it faces a program it's often dominated in coach Bob Stoops' tenure.
The 16th-ranked Sooners, though, will have to contend with a high-powered offense when they host Tulsa on Saturday.
Oklahoma (2-0) rallied from a 14-point deficit in the final 8 1/2 minutes last Saturday for a 31-24 double-overtime victory at then-No. 23 Tennessee. Baker Mayfield went 11 of 14 for 103 yards and three touchdowns in the final quarter and OT.
Sterling Shepard caught two of those scores, including the winning 18-yarder.
"It's one of the more special wins, maybe my favorite of all of them," Stoops said.
Mayfield also had a 1-yard scoring run in the first extra period in his second start for the Sooners. He threw two interceptions and was 8 for 25 for 84 yards in the first 45 minutes.
"When you can come through that way, it can really give your team a boost to know that you're always in it," Stoops said.
Oklahoma will next face a team it's beaten by an average of 38.3 points in the last eight meetings. The Sooners handed Tulsa a 52-7 home loss last Sept. 6, racking up 580 yards to top 500 for the fifth consecutive matchup.
In its first two games under coach Philip Montgomery, Tulsa has gained at least 600 yards - albeit against far less-heralded competition. The Golden Hurricane had 279 on the ground in a 40-21 victory at New Mexico last Saturday with Zack Langer and D'Angelo Brewer each topping 130.
Dane Evans threw for 321 yards and two touchdowns, giving him 745 yards in his first two games.
Seeking their best start since 2008 when they opened 8-0, the Golden Hurricane (2-0) take on an Oklahoma squad that ranks sixth against the pass at 106.5 yards allowed per game and 10th in total defense at 240.0.
Montgomery has plenty of recent experience playing at Oklahoma, having been an offensive coordinator at Baylor for seven seasons before coming to Tulsa.
"We're still a team that's growing. We're still learning about ourselves and learning about our football team," Montgomery said. "We've got a lot of things we have to correct but overall we're excited about the direction we're pushing.
"We've got a great opponent this week. It'll be tough going down there and playing in that environment."
Evans was 23 of 43 for 204 yards with one touchdown and two interceptions in last year's meeting, including one pick that was returned 45 yards for a score in the third quarter. Oklahoma scored the first 31 points en route to its 13th win in 14 matchups.
The Sooners have been ranked in all but two of those games and each of the last four. They were No. 4 in last year's trip to Tulsa.
Shepard had 177 yards and a TD on eight catches in last season's matchup, and 123 yards and two touchdowns on eight receptions in a 51-20 victory over the Golden Hurricane in September 2013. That was Oklahoma's 10th win in the last 11 home meetings.
Tulsa has lost six in a row to ranked teams - three of those coming against the Sooners.