Youngstown St. (2-1) quarterback Hunter Wells was 10 for 16 for 148 yards with a touchdown.
The Penguins built a 17-0 first quarter lead when Kuhn plunged 1 yard to score. In the second, Webb had a 20-yard run, Ruiz caught an 11-yard touchdown pass and Kuhn scored again from 6 yards to make it 38-0 before halftime.
Youngstown St. held the Red Flash (1-2) to 87 yards offense.
St. Francis' Zach Drayer completed 1 pass in 12 attempts for 10 yards. Marcus Bagley had 66 yards on 24 carries.
AP College Football website: www.collegefootball.ap.org