St. Francis (2-2) got off on the right foot, as Lorenzo Jerome returned the opening kickoff 98 yards for a touchdown and the Red Flash never looked back. Midway through the first, Miller grabbed an Austin Herink pass and went 40 yards the other way for a touchdown. Late in the second, Orsini picked off Nick Sexton and went 34 yards for a score.
Khairi Dickson, Zack Drayer, Wesley Nagaseu and Marcus Bagley ran for touchdowns, and Dreyer completed a 37-yard scoring pass to Terell Smith. Dreyer was 13 of 17 for 175 yards. Dickson finished with 72 yards on 13 carries and Smith had six catches for 148 yards.
East Tennessee (0-5) managed just 185 total yards.