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Week 3 betting guide: How to play the gambling odds this Saturday

All the odds, information and advice you'll need to make informed bets in Week 3 of the college football season.

The No. 9 USC Trojans are just 1-7 ATS in their last eight games as a road favorite. Coming off their big road upset over Stanford last week, the Trojans will be a 17-point road favorite against Boston College on Saturday.

The Eagles have put together a 4-1 ATS record in its last five games as home underdogs but but haven’t fared well against the Pac-12. Boston College is 0-5 ATS in its last five games against Pac-12 foes. The best play in this game could be on the OVER, which is 4-1 in USC's last five games as a road favorite and 5-1-1 in Boston College's last five games as a home underdog. The line is set at 51 points, according to sportsbooks monitored by OddsShark.com.

Week 3 college football picks: UCLA vs. Texas, Georgia at South Carolina

The No. 16 Arizona State Sun Devils could make for a strong play on the road as 15.5-point favorites against the Colorado Buffaloes. Arizona State is 6-0 SU and 5-1 ATS in its last six games as a road favorite. Colorado meanwhile is just 3-16 SU and 5-14 ATS in its last 19 home games against Pac-12 opponents.

The No. 11 Notre Dame Fighting Irish are 28-point home favorites hosting the Purdue Boilermakers on Saturday, according to sportsbooks monitored by OddsShark.com. Notre Dame is 4-1 ATS over its last five home games and looks like a strong pick after its 2-0 SU and ATS start this season. Purdue is just 2-6-1 ATS in its last nine games as an underdog.

No. 3 Alabama is 4-1 ATS in its last five games as a home favorite. The Crimson Tide host Southern Miss on Saturday as 47.5-point favorites. Southern Miss is just 2-9 ATS in its last 11 road games and 2-7 ATS in its last nine games as an underdog.

Trends point to the UNDER of 64 points when the Nevada Wolfpack visit the Arizona Wildcats. The UNDER is 5-1 in Arizona's last six games as a home favorite and 6-0 in Nevada's last six games as an underdog.

• RICKMAN: The TV guide to your perfect Week 3 college football Saturday