Three of the No. 1 seeds have survived heading into the Sweet 16 of the NCAA tournament, and the undefeated Kentucky Wildcats remain heavy favorites to cut down the nets at 1/1 odds at the sportsbooks as the top seed in the Midwest Region.
Kentucky and Arizona have been double-digit favorites in every one of their games so far, and they would square off against each other in the Final Four if both make it through the next two rounds unscathed.
Arizona was the top seed in the West a year ago but lost the Regional Final to the second-seeded Wisconsin Badgers (8/1), which are a No. 1 seed this year. Kentucky has a slightly easier road to the Final Four now that the second-seeded Kansas Jayhawks were knocked out by the seventh-seeded Wichita State Shockers (33/1) on Sunday.
Wichita State’s perfect season ended last year against Kentucky in the Round of 32, and the Shockers are hoping for a chance to return the favor in the Midwest Regional Final if they each advance through the Sweet 16. The third-seeded Notre Dame Fighting Irish (33/1) stand in Wichita State’s way while Kentucky has to get past the fifth-seeded West Virginia Mountaineers first as well; the Mountaineers are well back at 100/1 on the college basketball odds to win the tournament.
In the South Region, the top-seeded Duke Blue Devils (8/1) and second-seeded Gonzaga Bulldogs (12/1) are still on a collision course to meet in the Regional Final, with the fifth-seeded Utah Utes (20/1) and 11th-seeded UCLA Bruins (100/1) both hoping to derail that possibility. The Blue Devils seem to be the most likely candidate right now to advance to the national championship game from that side of the bracket.
With top-seeded Villanova and second-seeded Virginia already out of the East, the winner between the third-seeded Oklahoma Sooners (25/1) and seventh-seeded Michigan State Spartans (14/1) in the Sweet 16 figures to be the favorite to advance to the Final Four. Michigan State ousted Virginia for the second year in a row.
The other March Madness Sweet 16 matchup in the East pits the fourth-seeded Louisville Cardinals (25/1) against the eighth-seeded North Carolina State Wolfpack (50/1), which upset Villanova on the weekend.