There is only one game between Top 25 teams in Week 8 of the college football season, while the three best teams in the nation according to the AP poll get to play opponents with three losses or more.
That means there will be some major mismatches for bettors to handicap, as they decide whether to back heavy favorites or big underdogs at sportsbooks monitored by OddsShark.com.
The 15th-ranked Texas A&M Aggies (5-1) are coming off their first loss of the season last Saturday to the eighth-ranked Alabama Crimson Tide 41-23 at home as five-point underdogs, and oddsmakers believe they will fall again this week when they visit the 24th-ranked Ole Miss Rebels (5-2).
Texas A&M is a consensus six-point underdog at Ole Miss and has failed to cover the spread in each of the last three meetings. The Rebels are 4-0 straight-up at home and 3-1 against the spread this season but just suffered their second loss of the year on the road to the Memphis Tigers last week 37-24 as 10-point favorites. Ole Miss upset Alabama 43-37 as a nine-point dog in Week 2.
The second-ranked Baylor Bears (6-0) and third-ranked Utah Utes (6-0) keep stealing first-place votes from the top-ranked Ohio State Buckeyes (7-0), and two of the three teams are huge favorites in Week 8.
However, Utah is actually a 3.5-point road underdog visiting the struggling USC Trojans (3-3), who have lost two straight games to the Washington Huskies and Notre Dame Fighting Irish by a combined 15 points.
The Utes are riding an eight-game winning streak though and have gone 8-1 ATS in their last nine road games according to the OddsShark College Football Database, so maybe they can upset the Trojans for the second year in a row.
The Bears are massive 37-point favorites hosting the Iowa State Cyclones (2-4), who blew a 21-14 first-quarter lead against the fourth-ranked TCU Horned Frogs last week in a 45-21 loss. Baylor has covered four straight games and is averaging more than 65 points during that stretch. The Bears are also 15-5 ATS in their past 20 home games while the Cyclones have gone 2-9 versus the line in their last 11 overall.
Ohio State is a 21-point road favorite against the Rutgers Scarlet Knights (3-3), who just won a wild 55-52 affair against the Indiana Hoosiers. Indiana led 52-27 late in the third quarter before Rutgers reeled off 28 unanswered points to pull off the upset as a 6.5-point dog.
The Buckeyes beat the Penn State Nittany Lions 38-10 last week as 18-point home favorites, covering the spread for the first time since their season opener.