With odds of -150, Najee Harris is the current favorite to be the first rusher taken in the 2021 NFL Draft. . Following the Alabama product is Clemson’s Travis Etienne at +150 and North Carolina’s Javonte Williams at +400. The Over/Under for running backs to go in round one is set at .5 which is on par with the most recent draft day trends. Sports Illustrated’s Michael Fabiano and Frank Taddeo discuss this group of incoming rookie running backs and predict which team may grab them.