Jason Arnott and David Legwand each had a goal and two assists as Nashville had its highest-scoring game since a 9-4 win over Calgary last March 18.
Steve Sullivan, Josef Vasicek and Ryan Suter also scored for Nashville, which pulled two points ahead of Detroit and into first place in the Central Division.
Tony Salmelainen scored twice for the Blackhawks, who surrendered the most goals in a game since a 9-1 loss at Dallas on Nov. 4, 2005. Brandon Bochenski added a goal for Chicago.
Chris Mason made 35 saves in his 20th straight start. He has started every game for the Predators since top goalie Tomas Vokoun underwent thumb surgery on Nov. 27.
Nikolai Khabibulin started for Chicago, but was replaced by Brian Boucher at 1:13 of the second after allowing four goals on 13 shots. Boucher yielded four goals on 17 shots.
All 11 goals in the game were scored at even strength.