Ramirez, who homered in the third, was hit by T.J. House's pitch with a runner on first and two outs. He limped a couple of feet from home plate and went to the ground, writhing in pain. Manager Robin Ventura and a team trainer quickly came on the field as Ramirez grabbed his foot.
Ramirez slowly walked off the field and angrily fired his helmet into the dugout.
Leury Gracia pinch ran for Ramirez and remained in the game at shortstop.