Buffalo's O.J. Simpson rushes for a then-NFL record 250 yards in Buffalo's 31-13 victory at New England.
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At Yankee Stadium, the Bronx Bombers hold Catfish Hunter Day to honor their future Hall of Fame pitcher who will be retiring at the end of the season at the age of 33.
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Atlanta's Otis Nixon is suspended for the rest of the 1991 season after cocaine was found in his system during a drug test.
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Diamondback righty Curt Schilling strikes out his 300th victim to join Randy Johnson in becoming the first teammates to each strike out at least 300 batters in the same season.
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In a dramatic at bat, Jim Thome becomes the 23rd overall to hit 500 career home runs. The historic homer comes in the bottom of the ninth on a full count as the White Sox DH strokes a two-run walkoff round tripper to beat the Angels at U.S. Cellular Field, 9-7 .
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In a 1-0 victory over the Dodgers, Reds pitcher Tom Browning pitches the 12th perfect game in major league baseball.