Love, averaging 17 points and 10.4 rebounds, was injured in Wednesday's win over Miami. He was accidentally poked in the eye by the Heat's Mario Chalmers while going for a rebound early in the third quarter and went down in extreme pain.
He was re-examined in Chicago. Tristan Thompson started in Love's place.
Cleveland had won 14 of 15 and trailed Chicago by a half-game in the Central division entering Thursday's matchup.