All three left the field in the second quarter, and the Saints did not announce their status until early in the third quarter.
Graham had two catches for 36 yards, including a 23-yard grab on his first play after the injury occurred.
Graham injured his right shoulder in the first quarter and came to the sideline to be checked by trainers, but returned for a couple more offensive series before leaving for good. Goodwin hurt his knee and Humber his ankle later in the quarter.
The Saints have a bye next week.
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