The San Francisco 49ers (4-4) will try to break a two-game losing when they take on NFC South leader New Orleans, which has a two-game winning streak of their own.
The second half of the season should be favorable to the Saints, as they play five of its last eight games at the Superdome. New Orleans has won 11 straight at home, which is the third-longest current streak in the NFL.
You can follow the game with live stats and play-by-play here.
How to watch
Details for Thursday's game are below:
Kickoff: 1 p.m. ET
Live stream: The game can be streamed live here.
TV coverage: FOX
How they've fared
San Francisco 49ers
Week 9: Rams 13, 49ers 10
In a rematch of a Week 6 contest, the Rams sacked Colin Kaepernick eight times. The game hinged on two plays: 49ers punter Andy Lee's shanked 23 yards punt that led the Rams game-winning field goal with five minutes left and Kaepernick fumbling at the goal line with two seconds left when he tried to sneak in for the go-ahead touchdown.
Week 8: Bye
Week 7: Broncos 42, 49ers 17
Denver put the game away in the third quarter, scoring three touchdowns on two Ronnie Hillman runs and another Demaryius Thomas scoring strike to take a commanding 42-10 lead. While the Broncos offense could not be stopped, the defense stood tall as well, sacking Colin Kaepernick six times and holding San Francisco to 62 yards rushing.
Week 6: 49ers 31, Rams 17
Colin Kaepernick threw for 348 yards and three touchdowns to three different receivers and the defense sacked St. Louis quarterback Austin Davis five times as the 49ers overcame a 14-point first quarter deficit. San Francisco came into the contest with only five sacks through the first five games.
St. Louis got the ball back trailing by seven with less than two minutes remaining in the game, but Davis was picked off by defensive back Dontae Johnson, icing the game. San Francisco receiver Anquan Boldin led a dominant passing attack with seven catches for 94 yards.
New Orleans Saints
Week 9: Saints 28, Panthers 10
The Saints took advantage of a Panthers offensive line that was missing three starters. The defense sacked Cam Newton four times and held him 122 yards passing and a career-low 35.7 percent completion percentage.
Week 8: Saints 44, Packers 23
The two quarterbacks, Drew Brees and Aaron Rodgers, combined for 700 yards passing, but Brees and the Saints routed Green Bay to break the Packers' four-game winning streak. Aaron Rodgers was picked off twice and sacked three times, but he still threw for 418 yards.
The game was the third in NFL history in which neither time punted the ball. It also happened earlier this season in Green Bay's 38-17 victory over Chicago in Week 4.
Week 7: Lions 24, Saints 23
Drew Brees' interception late in the fourth quarter led to a stunning comeback by Detroit, by erasing a 13-point lead with less than four minutes, capped off by Matthew Stafford's five-yard touchdown pass to Corey Fuller with 1:48 left. Detroit receiver Golden Tate set career highs with 10 receptions for 154 yards, and Detroit's No. 1 ranked defense held up when they needed. The loss to Detroit was the Saints seventh straight on the road.