ORCHARD PARK, N.Y. (AP) The preseason game against the New York Giants became secondary to Bills defensive tackle Kyle Williams once he learned teammate Marcell Dareus was entering rehab and Karlos Williams was cut.
''All know is that when someone gets to the point when they say, `Hey I need help,' then it must be a big problem,'' Williams said, noting Bills owners Terry and Kim Pegula played a role in counseling Dareus to seek help. ''I care more about him than I do his football career, so I want to see him better.''
Dareus, the Bills' top-paid player, announced an hour before Buffalo's 21-0 win on Saturday he was entering rehab.
The decision came four days after he was suspended for four games by the NFL for violating the league's substance abuse policy for a second consecutive season.
As for Karlos Williams, Kyle Williams hoped for the best regarding the backup running back who has battled offseason weight issues and also was suspended for violating the substance abuse policy.
''Hopefully, what happened today may be a wakeup call for him,'' Williams said.
On the field, the ''Bad News'' Bills (1-1) overcame their latest series of preseason distractions by dominating the sloppy Giants (0-2).
Tyrod Taylor zipped a 13-yard touchdown pass over the middle to LeSean McCoy to cap his fourth and final series. Backup EJ Manuel then secured the win by leading two touchdown drives. Rookie running back Jonathan Williams scored on a 1-yard plunge and Manuel completed a 19-yard touchdown pass to Greg Little.
For New York, quarterback Eli Manning and receiver Odell Beckham Jr.'s preseason debut failed to provide the Giants any boost, a week following a 27-10 loss to Miami.
Manning completed 4 of 9 passes for 44 yards in four series, in which New York combined for 33 yards of offense and one first down. Beckham had one catch for 33 yards, and was targeted three times.
''You can't freak out, but there's got to be some urgency, and we have to do things better than we did today,'' Manning said.
First-year Giants coach Ben McAdoo was more blunt.
McAdoo gave a one-word answer, ''No,'' when asked if he saw any positives from an offense that managed seven first downs and 166 yards - a third of those coming on Bobby Rainey's 67-yard run in the fourth quarter.
Turnovers continued to be an issue.
Backup quarterback Ryan Nassib lost a fumble. Against Miami, he threw two interceptions and lost one of three fumbles. He missed his first seven attempts and finished 2 of 12 for 25 yards.
Backup running back Andre Williams lost a fumble and third-string quarterback Logan Thomas threw two interceptions.
Giants: First-round pick, CB Eli Apple, did not play after hurting his knee against Miami. Second-round pick, WR Sterling Shepard, had Manning's pass over the middle go off his fingers.
Bills: Third-round pick, DT Adolphus Washington, recovered a fumble when Nassib was sacked by defensive back Sterling Moore.
Giants: WR Dwayne Harris hurt his knee and did not return after returning a punt early in the second quarter. The Giants said tests were negative. S Mykkele Thompson sustained a concussion when lowering his head to tackle RB Jonathan Williams late in the second quarter.
Bills: Backup RB Mike Gillislee was being evaluated for a concussion after being hurt on a 6-yard run in the second quarter.
Bills PK Jordan Gay's chances of supplanting veteran Dan Carpenter took a hit. Gay missed one of two extra-point attempts and missed a 37-yard field-goal attempt. He hit the right crossbar on both misses.
Giants PK Tom Obarski missed a 27-yard field-goal attempt wide left. Obarski is competing to fill in for Josh Brown, who will open the season serving a one-game suspension for violating the NFL's personal conduct policy.
Bills special teams quality control coach Kathryn Smith, the NFL's first full-time female assistant coach, was on the sideline, and Sarah Thomas, the NFL's first full-time female official, was on the field as a line judge. This is the second time a female assistant and official were on the field at the same time. Last summer, Thomas officiated an Arizona preseason game during Jen Salter's six-week training camp internship coaching Cardinals linebackers.
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