Before Sunday night, Manning had never lost a game in which he led by at least 22 points, going 50-0 in the regular season in that scenario, and 2-0 in the playoffs. So 52-0 with that type of three-touchdown-plus lead (the Broncos led 24-0 at halftime), and for all places for that streak to end, it came in Manning's personal House of Horrors (Gillette Stadium), against Brady, his longtime nemesis. We keep billing it as the best quarterback rivalry in NFL history, but Brady keeps making sure it's pretty one-sided. It's 10-4 now in Brady's favor, and No. 12 had by far the better night, completing 34-of-50 passes for 344 yards, with three touchdowns, no interceptions and a 107.4 passer rating. Manning turned in his worst game of the season, throwing for just 150 yards on 19-of-34 passing, with two touchdowns, one interception and a 70.4 rating. SI.com looks back at the Brady-Manning rivalry, starting from the beginning...
2 of 14Damian Strohmeyer/SI
Sept. 30, 2001
The Brady-Manning rivalry began on a positive note for the Patriots. In Brady's first NFL start, Manning threw three interceptions in an easy New England victory.
3 of 14John Ruthroff/AFP/Getty Images
Oct. 21, 2001
Brady was brilliant in his second game against Indy, completing 16-of-20 passes for 202 yards, three touchdowns and no interceptions in another rout.
4 of 14Andy Lyons/Getty Images, AP
Nov. 30, 2003
The Pats' withstood a four-touchdown performance by Manning to hold on for a close win. New England's Bethel Johnson had a 92-yard kick return for a touchdown to end the first half and a 67-yard return in the fourth quarter that changed the tide of the game.
5 of 14Peter Read Miller, John Iacono/SI
Jan. 18, 2004
Ty Law had three of New England's four interceptions of Manning, and Brady was coolly efficient in helping the Pats advance to Super Bowl XXXVIII.
6 of 14AP
Sept. 9, 2004
The Patriots kicked off the 2004 season with another win over the Colts. This time it came down to the wire, but a New England defense that had struggled all night came up tough in crunch time to preserve the win.
7 of 14Simon Bruty/SI
Jan. 16, 2005
Once again, the Patriots shut down Manning, using their ball-control offense to perfection on a freezing night in Foxboro.
8 of 14Damian Strohmeyer, Al Tielemans/SI
Nov. 7, 2005
Manning entered the game 0-7 in his career at Foxboro, but he completed 28-of-37 passes for 321 yards, three touchdowns and just one interception to finally beat the Patriots on the road.
9 of 14Damian Strohmeyer/SI
Nov. 5, 2006
The defense intercepted Brady four times and Manning threw two touchdowns to Marvin Harrison to help the Colts improve to 8-0.
10 of 14Bill Frakes, Damian Strohmeyer/SI
Jan. 21, 2007
The Patriots suffered their most devastating defeat of the Brady-Belichick era with a spectacular collapse in the AFC Championship Game against the Colts. Manning threw for 349 yards (137 to tight end Dallas Clark) and rallied Indianapolis from a 21-3 deficit to secure the improbable victory -- completing the biggest comeback in conference title-game history.
11 of 14Al Tielemans/SI
Nov. 4, 2007
The Patriots stayed on course for an unbeaten season (9-0) as Brady threw two of his three touchdown passes in a four-minute span in the fourth quarter to overcome a 10-point deficit and beat Super Bowl champion Manning and the Colts, 24-20.
12 of 14David E. Klutho, Damian Strohmeyer/SI (2)
Nov. 15, 2009
Trailing 31-14 in the fourth quarter, the Colts mounted a spirited comeback, highlighted by a defensive stop on 4th-and-2 with 1:57 remaining (left inset). That gave Indy the ball with a short field at the 29, and Peyton Manning needed only four plays to score (right inset). Matt Stover hit the game-winning extra point.
13 of 14Charles Krupa/AP
Nov. 21, 2010
Brady had only six incompletions in 25 passes and threw for two TDs as the Patriots built a 17-point lead and held on. Manning finished 38-of-52 for 396 yards, four TDs and three interceptions. He got the Colts within three with 4:46 left on an 18-yard pass to Blair White, who earlier in the fourth quarter caught a 5-yard TD toss. Manning later brought them within range of a stunning win before James Sanders' interception at the New England 6 with 31 seconds remaining.
14 of 14Winslow Townson/SI
Oct. 7, 2012
In the first matchup following Manning's move from Indianapolis to Denver, Brady's Patriots rolled to a 31-21 victory over the Broncos. Brady finished 23-of-31, with 223 yards passing and two touchdowns (one passing, one rushing), moving to 9-4 all time against Manning. "Nobody I'd rather have than Tom Brady," Patriots coach Bill Belichick said after the game. "But Manning's a great player." Manning, who sat out the entire 2011 season with a neck injury, went 31-of-44 for 345 yards and three touchdowns.
You May Like
Sign Up for our Newsletter
Don't get stuck on the sidelines! Sign up to get exclusives, daily highlights, analysis and more—delivered right to your inbox!