Fisher hasn't played since he left Game 1 last Wednesday night with a lower-body injury. The Predators say the 34-year-old center is day to day.
Fisher had 19 goals and 20 assists in 59 games this season.
Nashville also played without defenseman Shea Weber on Tuesday night. Weber left Game 2 with a lower-body injury and did not travel to Chicago.
The team says it plans to provide an update on Weber's status on Wednesday. Game 5 is Thursday night in Nashville.