AS Roma vs. CSKA Moscow
Roma has not played in the Champions League tournament since the 2010-11 season, when they made it to the Round of 16. Last season, Roma finished in second place in Serie A. The club is currently tied at the top of the table, with a record of 2-0.
Moscow's last Champions League appearance came in 2011-12. The club finished second in the group stage, but lost to Real Madrid in the Round of 16. This season, CSKA Moscow is tied for second place in the Russian Premier League at 5-0-2.
Roma and CSKA Moscow have played six times. Roma has won five out of the six matches.
Time: 7:45 p.m. BST/2:45 p.m. ET.
Wednesday's full Champions League schedule
All times Eastern
Chelsea vs. Schalke 04, 2:45 p.m.
Porto vs. BATE Borisov, 2:45 p.m.
Roma vs. CSKA Moscow, 2:45 p.m.
Bayern Munich vs. Manchester City, 2:45 p.m.
Barcelona vs. Apoel Nicosia, 2:45 p.m.
Ajax vs. Paris Saint-Germain, 2:45 p.m.
Maribor vs. Sporting CP, 2:45 p.m.
Athletic Bilbao vs. Shakhtar Donetsk, 2:45 p.m.
Tuesday's full Champions League results
Liverpool 2, Ludogorets 1
AS Monaco 1, Bayer Leverkusen 0
Galatasaray 1, Anderlecht 1
Borussia Dortmund 2, Arsenal 0
Real Madrid 5, FC Basel 1
Zenit 2, Benfica 0
Juventus 2, Malmo 0
Olympiacos 3, Atletico Madrid 2