Defending champion Sevilla rescued a 2-2 draw at Rijeka in the Europa League, while Everton also snatched a point at impressive Russian side Krasnodar on Thursday.
Sevilla substitute Stephane Mbia leveled in stoppage time after Zoran Kvrzic's deflected shot appeared to have given the Croatian side the win. Iago Aspas gave Sevilla the lead in the 26th minute but the match was turned on its head shortly after halftime when Timothee Kolodziejczak was sent off for fouling Rijeka forward Andrej Kramaric, who fired in the spot kick.
Sevilla tops Group G by a point from Feyenoord, which beat Standard Liege 2-1. Liege was tied on points with Feyenoord.
In Group H, Everton has two more points than Krasnodar and Lille after the French side drew 1-1 at Wolfsburg. Krasnodar went close to taking all three points before Samuel Eto'o equalized with seven minutes remaining, guiding home Leighton Baines' cross from close range to spare Everton's blushes.
Everton defended poorly and gifted Krasnodar the lead shortly before halftime. Phil Jagielka attempted to clear Odil Ahmedov's pass but succeeded only in flicking the ball to Ari, who calmly slotted it past American goalkeeper Tim Howard. Krasnodar, which was founded only six years ago, could have doubled its lead after a fantastic run by another Brazilian, Wanderson, but he hit the crossbar.
In Germany, a stunning long-range volley from Kevin De Bruyne handed Wolfsburg a share of the spoils. Lille's Belgian international Divock Origi broke the deadlock from the penalty spot five minutes earlier following a Ricardo Rodriguez handball.
Marek Hamsik scored against his old club and set up another to help Napoli to a 2-0 win at Slovan Bratislava. Substitute Gonzalo Higuain headed in the second less than a minute after going on to see Napoli move to the top of Group I, as Sparta Prague beat Young Boys 3-1.
Fiorentina was also three points clear in its group following a comfortable 3-0 win at Dinamo Minsk, with goals from Alberto Aquilani, Josip Ilicic and 20-year-old Federico Bernardeschi. Guingamp secured a surprise 2-0 win over PAOK in Group K's other match.
Dinamo Moscow sprung a surprise in Group E, topping Eredivisie leader PSV Eindhoven 1-0 on Yuri Zhirkov's strike in the third minute of second-half stoppage time.
Tottenham blew a late lead against Besiktas at White Hart Lane, with Demba Ba's late penalty negating Harry Kane's opener in a 1-1 Group C draw.
In Group D, Kris Commons' sixth-minute goal was enough for Celtic to take a 1-0 win over Dinamo Zagreb, while Danilo D'Ambrosio and Mauro Icardi gave Inter Milan a 2-0 Group F win over Azerbaijan's Qarabag.
Villarreal ran away with a 4-0 Group A win over Apollon FC, as Javier Espinosa and Gerard Moreno each scored two goals. Mexico international Giovani dos Santos assisted on Moreno's second, in the 82nd minute.