Veteran forwards Blas Perez and Luis Tejada will look to guide Los Canaleros in a tough group featuring both 2015 Copa America finalists.
Panama manager Hernan Dario Gomez will bring a veteran squad to take on a tough group in Copa America Centenario.
Panama, which must play defending Copa America champion Chile, Lionel Messi's Argentina and Bolivia in Group D, will have the stalwart likes of Blas Perez, Luis Tejada, Felipe Baloy and Jaime Penedo suiting up this summer, one year after pipping the United States to a third-place finish in the CONCACAF Gold Cup.
San Jose Earthquakes midfield tandem Anibal Godoy and Alberto Quintero will also make the trip, although center back Roman Torres will not as he continues his recovery after suffering a long-term knee injury with the Seattle Sounders.
Here is Panama's roster in full:
GOALKEEPERS: Jose Calderon (Platense), Jaime Penedo (Saprissa), Alex Rodriguez (San Francisco FC)
DEFENDERS: Felipe Baloy (Atlas), Harold Cummings (Alajuelense), Erick Davis (FC DAC 1904), Fidel Escobar (Sporting San Miguelito), Luis Henriquez (Tauro FC), Adolfo Machado (Saprissa), Roderick Miller (San Francisco FC), Martin Gomez (San Francisco)
MIDFIELDERS: Ricardo Buitrago (Juan Aurich), Armando Cooper (Arabe Unido), Anibal Godoy (San Jose Earthquakes), Gabriel Gomez (Cartagines), Amilcar Henriquez (America FC), Valentin Pimentel (La Equidad), Alberto Quintero (San Jose Earthquakes)
FORWARDS: Abdiel Arroyo (RNK Split), Roberto Nurse (Mineros de Zacatecas), Blas Perez (Vancouver Whitecaps), Luis Tejada (Juan Aurich), Gabriel Torres (Zamora FC)