Sutton and Lincoln City are the two non-league sides remaining in the FA Cup.
Arsenal will play at non-league Sutton United in the FA Cup fifth round, headlining Monday's draw of the last 16 teams.
Sutton, which beat Leeds United 1-0 in the fourth round to advance, is one of two non-league sides in the final 16. The other, Lincoln City, will play at Burnley after beating Brighton & Hove Albion 3-1.
In addition to Arsenal, the other title-chasing Premier League powers that remain will all play away from home. Chelsea will head to Wolverhampton, which defeated Liverpool in the fourth round; Manchester United will play at Blackburn; Tottenham will head to Fulham in a London derby; and Manchester City will play at Huddersfield, which is coached by American David Wagner.
One place in the final 16 remains up for grabs, with Derby County and Leicester City forced into a replay.
Here are the full pairings:
Burnley vs. Lincoln City
Fulham vs. Tottenham
Blackburn Rovers vs. Manchester United
Sutton United vs. Arsenal
Middlesbrough vs. Oxford United
Wolverhampton vs. Chelsea
Huddersfield Town vs. Manchester City
Millwall vs. Derby County or Leicester City