Fifth-tier Luton became the first non-league club in 24 years to a beat top-level opponent in the FA Cup, defeating Norwich 1-0 in the fourth round Saturday on Scott Rendell's goal in the 80th minute.
Luton, which played in the second tier as recently as 2006-07, is 85 places below Norwich in the English soccer pyramid. There had not been such an upset in the FA Cup since Sutton beat Coventry 2-1 in the third round in 1989. Not since 1949 has a non-league team managed to overcome a top-level team after the third round.
Luton, an FA Cup semifinalist in 1994, won the League Cup in 1988 and was in the top division until 1992.
Third-tier MK Dons won 4-2 at Queens Park Rangers, which is last in the Premier League.
Manchester United routed visiting Fulham 4-1 and advanced to the final 16 as Ryan Giggs converted a third-minute penalty kick, Wayne Rooney doubled the lead in the 50th minute and Javier Hernandez added two goals.
Arsenal avoided an upset at Brighton by beating the second-tier club 3-2 as Theo Walcott scored a tiebreaking goal in the 85th minute.
Manchester City, the 2011 champion, won 1-0 at Stoke on Pablo Zabaleta's 85th-minute goal.
American midfielder Stuart Holden played his second game since a 16-month layoff caused by a knee injury, entering in the 81st minute of Bolton's 2-1 loss to visiting Everton. John Heitinga came in during the 80th minute for the Toffees and scored in injury time to give David Moyes a win in his 500th game as Everton manager.