Chelsea face Aston Villa in the third round of the Carabao Cup after an unbeaten start to the season.
With a change of competition, Tuchel has hinted at several changes to his starting XI.
Kepa; James, Chalobah, Sarr; Hudson-Odoi, Saul, Kante, Chilwell; Ziyech, Loftus-Cheek, Werner
Kepa is likely to keep his place in goal as Edouard Mendy is ruled out through injury.
A change of defence could see Reece James utilised in the back three alongside Trevoh Chalobah and debutant Malang Sarr as Tuchel could opt to rest his first choice central defenders ahead of the Blues' clash with Manchester City at the weekend.
James' central position could see Callum Hudson-Odoi given game time on the right whilst Saul Niguez returns for his second appearance following a disappointing debut in the league clash against Aston Villa.
N'Golo Kante only played 45 minutes at the weekend so could play alongside Saul as Ruben Loftus-Cheek takes up a more attacking role alongside Hakim Ziyech and Timo Werner.
Ben Chilwell is in line for his first start since the Champions League Final and the game could be the perfect opportunity for him to find fitness.
Ross Barkley could feature off the bench, if not chosen to start as the midfielder has been named in the squad.
Christian Pulisic will not make the squad after coming back from international duty with an injury.
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