Manchester United's clash with Liverpool is under threat following protests from the home fans.
The time has gone beyond kick-off time without a ball being kicked.
The disruption comes weeks after Manchester United's involvement in the European Super League.
United's fans gathered at Old Trafford in protest to their owners, the Glazers family, the spectators breached security and filtered onto the pitch.
Elsewhere, the demonstrations took place outside the Lowry Hotel in Salford where the Red Devils were preparing for the match with the Reds.
Ole Gunnar Solksjaer's side requires a point to delay city rivals Manchester City's title-winning party for another week after Pep Guardiola's side beat Crystal Palace 2-0, yesterday.
There is no confirmation on the rescheduled kick-off but reports suggest up to a two-hour delay, which means the revised start time is at least 6:30pm.
Both sets of players are still in their respective hotels, Sky Sports are inside the stadium, police are on the scene trying to disperse the crowds.
Michael Oliver, tonight's match referee, is at the ground but there are multiple reports that the team buses have avenues to the ground have been disrupted.
In the complexion of the Premier League table, it is a crucial game for Jurgen Klopp's side, a win could move the champions into fifth, four points off the top four with Chelsea occupying the final European spot.
The latest reports are that crowds are dispersing following police intervention.
The teams have been announced as Nathanial Phillips returns to the starting line-ups for the Reds.