No. 6 Juan Martin del Potro defeats No. 1 Roger Federer
Playing in his first Grand Slam final, the 20-year-old Argentine rallied to beat the five-time defending champion 3-6, 7-6 (5), 4-6, 7-6 (4), 6-2. In snapping Federer's 40-match winning streak at the tournament and denying him a third major this year, del Potro joined Guillermo Vilas (1977) as the only South Americans to win the Open.
2 of 10Jessica Kluetmeier/SI
No. 16 Marin Cilic defeats No. 2 Andy Murray
Cilic reached his first Grand Slam quarterfinal with a stunningly easy 7-5, 6-2, 6-2 victory against last year's runner-up. After leading 5-4 in the first set, Murray lost the next seven games and never recovered.
3 of 10Simon Bruty/SI
Kim Clijsters defeats No. 3 Venus Williams
Anyone wondering how serious a threat Clijsters might be after a two-year layoff got their answer Sunday, when the 2005 champion toppled Williams 6-0, 0-6, 6-4 to advance to the quarterfinals.
4 of 10Erick W. Rasco/SI
Melanie Oudin defeats No. 29 Maria Sharapova
The 70th-ranked Oudin (foreground), a 17-year-old from Marietta, Ga., pulled off her second shocker of Week 1 when she knocked off three-time Grand Slam champion and former No. 1 Sharapova 3-6, 6-4, 7-5 to reach the fourth round.
5 of 10Al Bello/Getty Images
John Isner defeats No. 5 Andy Roddick
Isner took out No. 5 seed and sentimental favorite Roddick 7-6 (3), 6-3, 3-6, 5-7, 7-6 (5) in the third round. The three hour, 51-minute marathon was the biggest victory of Isner's career.
6 of 10AP
Yaroslava Shvedova defeats No. 5 Jelena Jankovic
Shvedova, the world No. 55 from Kazakhstan, took out Jankovic in a third-set tiebreaker, 6-3, 6-7 , 7-6.
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Petra Kvitova defeats No. 1 Dinara Safina
Pushed off the main U.S. Open stadium court because of time concerns, Kvitova, ranked 72nd, upset Safina 6-4, 2-6, 7-6 (5). Safina lost three match points in the third set.
8 of 10AP
Melanie Oudin defeats No. 4 Elena Dementieva
Dealing with a leg injury and an overwhelming occasion on a supersized stage, Oudin stunned Dementieva 5-7, 6-4, 6-3 in Round 2.
9 of 10AP
Kateryna Bondarenko defeats No. 11 Ana Ivanovic
Bondarenko knocked out Ivanovic in the first round 2-6, 6-3, 7-6 (7). This wasn't considered a huge upset because Bondarenko entered the tournament in good form while former No. 1 Ivanovic has been struggling for a while.
10 of 10Simon Bruty/SI
Melanie Oudin defeats No. 13 Nadia Petrova
Oudin eliminated a ranked Russian for the third consecutive match, rallying to beat Petrova 1-6, 7-6 (2), 6-3 in the fourth round. The American improved to 17-4 in three-set matches this year.
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