Skip to main content
Publish date:

How to Watch San Francisco 49ers at Arizona Cardinals: Live Stream, TV Channel, Start Time

The 49ers travel to Arizona on Sunday to take on the only undefeated team left in the NFL, the Cardinals.

The Cardinals (4–0) have started the year undefeated with wins against the Titans, Vikings, Jaguars and Rams. They will put their undefeated record on the line Sunday against the 49ers (2–2).

San Francisco started the year with wins against the Lions and Eagles before dropping two games to the Packers and Seahawks.

How to Watch: 49ers vs. Cardinals

Game Date: Oct. 10, 2021

Game Time: 4:25 p.m. ET

TV: Fox

Live stream 49ers vs. Cardinals on fuboTV: Start with a 7-day free trial!

Arizona quarterback Kyler Murray is the current favorite to win the NFL MVP award this year. He has 1,273 passing yards (third-most in the NFL) and nine touchdowns through the air. He also has added 109 rushing yards.

Everyone around Murray is benefitting as well. Chase Edmonds has 255 rushing yards and James Conner has four touchdowns. Murray also boasts four receivers with over 200 yards this season: A.J. Green (248), Christian Kirk (244), DeAndre Hopkins (225) and Rondale Moore (211).

The 49ers will turn to rookie Trey Lance as the starting quarterback Sunday. Lance will make his first start in place of Jimmy Garoppolo, who will miss the game with a calf injury.

Regional restrictions may apply.

How To Watch


San Francisco 49ers at Arizona Cardinals

Live Stream: FUBOTV
(Sign up now for a free seven-day trial.)
Sports Illustrated may receive compensation for some links to products and services on this website.