Resident Evil 4 remake Chapter 16 walkthrough

Complete the final chapter of the Resident Evil 4 remake with our step-by-step guide

Contents

1. Escaping the Island – RE4 Remake
2. Lord Osmund Saddler fight – RE4 Remake
3. Jet Ski escape – RE4 Remake

We’re finally here, the final chapter. If you’re ready for a big boss encounter, then this is actually quite a short chapter. If you’re not, well, this is going to be a lot to deal with. This is the final chapter of Resident Evil 4 remake, and it ends with a big bioweapon to take down. Doesn’t it always?

In this guide, we’re breaking down everything you need to know to take down Resident Evil 4 remake Chapter 16 – just read through our guide below.

Make sure to read our full Resident Evil 4 remake walkthrough for everything you need to find treasures and complete requests like Blue Medallions and Clockwork Castellans.

Escaping the Island – RE4 Remake

You’ll wake up in Luis’s Laboratory, freshly cured of any plagas infections. Nice. There’s plenty of lore to read in this room and the next few, if you are interested. But now, it’s time to get out of here. Ashley can bring down a collapsible ladder in the next room, and then the two of you can begin to make your escape.

You’ll have to go back through the ruined Sanctuary, and you can pick up a unique treasure in here, too. Expect Novistadors.

Eventually, you will come to a merchant above the Loading Docks. This is the final fight, so make sure to tune up and repair your equipment as much as you can.

Lord Osmund Saddler fight – RE4 Remake

Once you jump on the elevator, it’s time to fight. Saddler has four big weak points – the eyes on his legs. As soon as he drops down, detonate the red barrel near the start and you will be able to take out one or perhaps even two eyes at once. Once the eyes are down, Saddler’s head will lower, giving you a chance to either unload bullets into his mouth-eye thing, or go for a melee stab.

The arena is one of the toughest parts of this fight, as Saddler will break bridges, making it tough to run. There are supplies to find, but you might struggle to find a chance to grab them. You can drop down the ledge either next to where you start, or on the other side of this raised platform. The drop next to the start can’t be escaped from aside from a bridge which must be raised, is timed, and won’t go back up immediately, so it can put you in a very bad position.

The other drop has a ladder to get back up, and another raised area you can climb to get to the other side of the structure. This side of the arena is definitely the safest in terms of space to move.

Saddler has multiple swipe attacks, which will give you a dodge prompt. He also has two long-range attacks where he spits mucus. The horizontal version of this attack can be crouched under, though you should watch for a second burst. The vertical version of this attack can only be dodged while strafing.

Saddler will summon Novistadors during the fight, which is going to make things more difficult, though they will luckily die with just a single hit. Make sure to keep yourself healed, aim for the eyes, and pick up as much as you can in terms of supplies.

Eventually, Saddler will go down, leaving just a big glowing orb thing. Now you need to unload all of your remaining bullets while avoiding some tentacles. You’ll get dodge prompts, and if a tentacle appears on the left, you should strafe to the right, and vice versa.

Ada will throw down a rocket launcher. Grab it and fire it right at the orb. That’ll take down Osmund Saddler for good.

Jet Ski escape – RE4 Remake

Once the fight is over Ada will toss you some keys – it’s time to escape the Island before it explodes, like this is Sonic Adventure 2 or something. There’s also a Clockwork Castellan hidden in this section.

As you regain control, you’ll be in a long cave. Use the save point and start sprinting. Don’t worry about enemies you encounter, as they won’t actually fight you. The first door you come up against will have an enemy burst out – just step to the side of it to avoid that.

Eventually, you’ll come to the jet ski. In this section, you just need to hold accelerate while avoiding obstacles. Don’t the walls, don’t hit the things in the water other than yellow ramps, and you’ll make it in plenty of time.

Once you make it out of the jet ski section, Chapter 16 will be complete, as will the entire game!

Make sure to read our full Resident Evil 4 remake walkthrough to check for anything you missed during your playthrough!