CHICAGO (AP) Megan Podkowa and Jessica January each scored 16 points to help No. 24 DePaul beat Creighton 81-63 on Friday night for its fourth straight win in the series.
Podkowa was 7 of 10 from the field and January had seven rebounds, seven assists and four steals.
DePaul broke it open with a 31-11 second quarter in which Podkowa scored nine points and January had six.
Chanise Jenkins added 11 points, six rebounds and seven assists for DePaul (15-6, 7-1 Big East), which leads the conference as its only one-loss team.
Freshman Audrey Faber narrowly missed her first double-double with 17 points and eight rebounds for Creighton (10-10, 4-4), which had a four-game winning streak snapped. Faber was 7 of 10 from the free-throw line as the Bluejays made 20 of 27 compared to 8 of 11 for DePaul.