Betting lines, point spread for San Diego State vs. California Week 4 college football game

Golden Bears are big favorites over the Aztecs

San Diego State Aztecs quarterback Jayden Denegal. | James Snook-Imagn Images

San Diego State will host California in a Week 4 rematch of a game won by the Golden Bears last year in Berkeley. 

There’s history on SDSU’s side. The home team has never lost in the series, which Cal leads 5-4. The Aztecs beat the Golden Bears 45-40 in San Diego in 2016.

However, oddsmakers from FanDuel Sportsbook set the betting line for Saturday's matchup at Snapdragon Stadium with Cal checking in as a solid betting favorite over San Diego State. 

Fresh off their third straight double-digit win, the Golden Bears (3-0) opened as a 12.5-point favorite over the Aztecs (1-1), who are coming off a bye week. San Diego State is trying to get back on its feet following a 36-13 loss at Washington State. 

The Golden Bears are 2-1 against the spread and 3-0 on the moneyline. They have been impressive in dominating their opponents this year, winning their opener on the road against former Pac-12 rival Oregon State 34-15 before claiming home wins against FCS Texas Southern, 35-3, and Minnesota of the Big Ten, 27-14. 

Sep 6, 2025; Berkeley, California, USA; California Golden Bears defensive backs Brent Austin (4) and Hezekiah Masses (5) react after a defensive play during the fourth quarter against the Texas Southern Tigers at California Memorial Stadium. | Darren Yamashita-Imagn Images

Last year, the Golden Bears led the Aztecs 7-3 at the half before scoring on their first four possessions of the second half for a 31-10 win. It was a sloppy game, as the teams combined for 27 penalties for 237 yards, including 15 penalties for 120 yards for the Aztecs.

San Diego State is 1-1 against the spread and on the moneyline. The Aztecs had no trouble covering in a 42-0 season-opening win against Stony Brook. But they struggled badly at Washington State, taking a 7-0 lead five minutes in before allowing the Cougars to score 29 straight points. 

Here's a closer look at the betting odds and point spread from FanDuel.

Cal vs. San Diego State Odds, Spread and Total

Spread:

• Cal: -12.5 (-112)
• San Diego State: +12.5 (-108)

Moneyline:

• Cal: -520
• San Diego State: +385

Total: 48.5 (Over -106/Under -114

Odds courtesy of FanDuel Sportsbook

Cal vs. San Diego State betting trends

Cal

• Record against spread: 2-1
• Moneyline: 3-0
• Over-under: 0-3

San Diego State

• Record against spread: 1-1
• Moneyline: 1-1
• Over-under: 1-1

• Percentage of bets on spread: Cal (79%)

Cal vs. San Diego State How to Watch

• Date: Saturday, Sept. 20
• Game Time: 7:30 p.m. PT
• Where: Snapdragon Stadium
• How to watch (TV): CBS Sports Network

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Odds courtesy of FanDuel Sportsbook. Game odds refresh periodically and are subject to change. If you or someone you know has a gambling problem and wants help, call 1-800-GAMBLER.