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After failing to move up one more spot before the 2021-2022 regular season concluded, the Philadelphia 76ers notched the fourth seed in the Eastern Conference last Sunday night after a blowout victory against the Detroit Pistons.

By picking up the fourth seed, the Sixers knew right away that they would face the Toronto Raptors in the first round of the playoffs. 

While the first-round series won't necessarily mirror the second-round series between the Sixers and the Raptors series from three years ago, there is cause for concern on the Sixers' end as Game 1 approaches on Saturday night.

This season, the Sixers and the Raptors played each other four times. In the first outing, Philadelphia missed its star center Joel Embiid. In addition, James Harden was still a member of the Brooklyn Nets, and Ben Simmons was an inactive member of the Sixers. 

As we've learned many times throughout the season, when Embiid is off the floor for the Sixers, the team struggles to hit its stride. Therefore, the first of four matchups between Philadelphia and Toronto resulted in a Raptors victory.

One month later, Embiid was back on the floor and helped lead the Sixers to a 114-109 victory with a 36-point outing. Three months later, the Sixers and the Raptors met for the third time this year. At that point, Embiid was healthy, and Harden was an active member of the Sixers. Although Philly had both stars on board, the Raptors got the best of them and handed the Sixers a loss while shorthanded.

Then during the final week of the regular season, the Sixers and the Raptors met for the fourth and final time. Although the Sixers got off to a hot start, creating a 15-point cushion for themselves in the first quarter, they quickly dropped their double-digit lead and took on a disappointing 119-114 loss.

The regular season and the playoffs are two different beasts. Therefore, the Sixers shouldn't think about going 1-3 against Toronto when their series begins on Saturday. While Philadelphia will still enter the series as favorites from the jump, they'll need several players beyond the stars to step up and help contribute to wins.

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Justin Grasso covers the Philadelphia 76ers for Sports Illustrated. You can follow him for live updates on Twitter: @JGrasso_.