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49ers vs. Seahawks Prediction, Best Bets & Odds for 11/23

The NFC West has become one of the most high-profile divisions, primarily thanks to the San Francisco 49ers continuing to be one of the top Super Bowl contenders, so it’s no surprise that their matchup with the Seattle Seahawks is the featured night game of the Thanksgiving Day slate. To help get you ready for the rivalry, we’ve provided our experts’ best 49ers vs. Seahawks prediction.

On top of the top pick from our 49ers vs. Seahawks best bets will be the full details regarding the newest FanDuel Sportsbook sign-up bonus.

49ERS VS. SEAHAWKS PREDICTION: San Francisco ML (-300 at FanDuel)

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San Francisco 49ers vs. Seattle Seahawks Prediction for Thanksgiving on Thursday, November 23rd

After starting the season 5-0 and living up to the hype of being one of the favorites to represent the NFC in Super Bowl 58, the 49ers went through their three-game losing skid. However, it’s safe to say that was primarily due to injury.

We can confidently say that for two reasons. Firstly, it was RB Christian McCaffrey, OT Trent Williams and WR Deebo Samuel that were injured - arguably the three most significant offensive players. Secondly, as soon as they had their bye week to get healthy, San Francisco went cross country to smack the Jacksonville Jaguars 34-3.

Along with a 13-point win just this past Sunday, our 49ers vs. Seahawks prediction is focused on them advancing to 8-3.

49ers vs. Seahawks Best Bets & Free Picks

Not only have the 49ers looked as hot as ever after their bye week, but the Seahawks have also been looking rough ever since the 37-3 beatdown they received courtesy of the Baltimore Ravens. They returned home to barely squeak out a win over the Washington Commanders, but that was far from impressive.

Then, just this past weekend, they blew a fourth-quarter lead - their league-leading eighth of the season - in a loss to the Los Angeles Rams, who are still below .500 even after that victory. Therefore, we expect the 49ers to continue their dominance over Seattle. In their last three meetings, San Francisco has come out on top.

Not only that, but they also covered the spread in all three of those games. They were even favorites of 8.5 and 9.5 points in two of them, winning those games by 20 and 18 points, respectively. In other words, they aren’t even allowing Seattle to keep things close. With that in mind, we’ll confidently make our best 49ers vs. Seahawks prediction on San Francisco ML (-300 at FanDuel Sportsbook).

How to Nab a $150 Bonus Betting on the 49ers ML at FanDuel Sportsbook

Our 49ers vs. Seahawks prediction could be the perfect opportunity to claim the latest FanDuel promo, and we’ve explained how for you below:

  1. ➡️ Register here ⬅️ for a new FD account without needing a FanDuel promo code
  2. Make an initial deposit of $10+
  3. Bet $5+ on any pre-game money line

As long as the team you targeted wins their contest, you’ll receive $150 in bonus bets, effectively getting you 30/1 odds, even on a huge favorite. That’s why our 49ers vs. Seahawks prediction could be the perfect opportunity, as it gets San Francisco at much more valuable odds. 

Even if you end up finding a different team to go with, make sure you join FanDuel today or check out all the matchups available to you.

49ers vs. Seahawks Betting Odds & Lines via FanDuel Sportsbook for Thanksgiving on Thursday, November 23rd, 2023

Using the 49ers vs. Seahawks odds at FanDuel Sportsbook below, a $30 wager on our 49ers vs. Seahawks prediction profits $10 as long as San Francisco wins, but remember, you can grab $150 in bonus bets on top of that as well.

Point Spread:

  • San Francisco 49ers -7 (-110) vs. Seattle Seahawks +7 (-110)

Money Line:

  • San Francisco 49ers (-300) vs. Seattle Seahawks (+245)

Game Total (Over/Under):

  • Over 43.5 (-110) vs. Under 43.5 (-110)

San Francisco 49ers: Jason Verrett Set to Join Practice Squad

Before you lock in any 49ers vs. Seahawks best bets, it’s also worth noting a recent acquisition for San Francisco. It’s only to the practice squad, but they’re looking to add CB depth with Jason Verrett, who they’re very familiar with.

The former Los Angeles Chargers spent the past few seasons with the 49ers before back-to-back ACL and Achilles tears impacted his career. Either way, it’s a small step in rejoining the team, and San Francisco is known for its defense as it is.

That stout defense is just one of several reasons we’re backing them with our 49ers vs. Seahawks prediction, and you can too at 30/1 odds when you become a new member at FanDuel for their ‘Bet $5, get $150’ sign-up bonus.

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