The Best Resveratrol Supplements on the Market in 2024

Resveratrol is a powerful antioxidant with many health benefits that include anti-aging. Here’s how to choose a resveratrol supplement that’s right for you.

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You may have heard that a glass of red wine is good for the heart, and there’s plenty of truth to this popular belief. Red wine is rich in resveratrol, a naturally occurring powerful antioxidant found in numerous plant sources like red grapes, apples and blueberries. As one of the most extensively-studied bioactive compounds in food, research shows that resveratrol can improve brain function, lower blood pressure, reduce inflammation and slow down the aging process.

Nowadays, increasing your resveratrol intake is much easier. Resveratrol supplements offer a high dose of resveratrol and pack in potent antioxidants that people use for numerous reasons, such as preventing cardiovascular disease as part of a heart-healthy diet or fighting drug resistance in cancer cells. Others turn to resveratrol supplements to manage blood sugar levels and reduce cholesterol.

Still, with so many resveratrol products on the market that range in purity, dose and quality, it can be tough to determine which supplement is right for you. Our best resveratrol supplements guide will highlight the top products of 2024, their pros and cons and key ingredients to help you make the right decision. We’ll also ask nutritionists what to be aware of before starting a resveratrol supplement.

Our Picks for Best Resveratrol:

• Thorne Research ResveraCel
• Cymbiotika NMN
• Zhou Nutrition Resveratrol
• Garden of Life RAW Resveratrol
• Life Extension Optimized Resveratrol Elite
• MRM Nutrition Resveratrol
• NOW Foods Resveratrol

Thorne Research ResveraCel

Thorne

Key features & specs

• Resveratrol purity: Undisclosed
• Resveratrol per dose: 150 milligrams
• Certifications: Gluten-free, dairy-free and soy-free
• Subscription: One to six months with 5% off every Autoship & Save order
• Key ingredients: Nicotinamide riboside hydrogen malate, quercetin phytosome, trans-resveratrol and betaine anhydrous
• Sweeteners: None
• Best for: Anti-aging and regulating metabolism
• Price per serving: $0.90

Thorne Research ResveraCel is a resveratrol supplement that hones in on anti-aging. As one of two resveratrol products from the popular supplement brand, which relies heavily on science to inform and build its products, this multi-faceted dietary supplement includes a mix of ingredients that all promote healthy aging. Its star ingredient is 415 milligrams of nicotinamide riboside hydrogen malate, a naturally-occurring form of Vitamin B3 that helps protect the brain, followed by 250 milligrams of Quercetin Phytosome, a powerful antioxidant that helps prevent disease. Then, there are 150 milligrams of trans-resveratrol, the compound’s digestible form.

This supplement is geared for individuals above the age of 35. “Thorne Research ResveraCel may be beneficial for individuals looking for a supplement that supports both anti-aging and energy metabolism,” explains dietitian and nutritionist Melissa Baker, RDN. (In simpler terms, energy metabolism is the process of changing food into energy.) While the 150-milligram dose of resveratrol is effective, it makes up only 16 percent of the product, so it’s important to do your research on the additional ingredients if you’re considering taking this particular supplement.

Thorne Research ResveraCel is designed to promote cellular repair, regulate hormones and even support menopause—making it one of the most well-rounded supplements on our list. It comes in capsule form, and is meant to be taken in two capsules one-to-two times daily. While this supplement can get a little pricey and costs $54 for 60 capsules, you can opt for an Autoship & Save subscription that saves you 5% on each order. “Overall, I felt more energetic by supplementing once a day,” writes a customer named Robert. “I also felt less tired and it lowered my appetite.”

Related Post: Thorne Supplements Review

Pros:

• Free from common allergens like gluten, dairy and soy
• Includes multiple anti-aging ingredients
• Regulates metabolism and hormones
• No sweeteners or added sugar

Cons:

• Resveratrol makes up just 16 percent of the product
• Label doesn’t disclose purity of resveratrol
• Runs on the expensive side

Cymbiotika NMN

Cymbiotika

Key features & specs

• Resveratrol purity: 98 percent
• Resveratrol per dose: 100 milligrams
• Certifications: None
• Subscription: Monthly with 10% off every Subscribe & Save order
• Key ingredients: Nicotinamide mononucleotide, apigenin, green tea extract, resveratrol and green coffee bean
• Sweeteners: None
• Best for: Energy and reducing oxidative stress
• Price per serving: $2.57

Cymbiotika NMN is a blend of nicotinamide mononucleotide (NMN) and resveratrol that’s designed to give a major energy boost. This San Diego-based supplement company produces a wide variety of products that are informed by a board of advisors made up of four leading doctors. The main ingredient in this supplement blend is 400 milligrams of NMN, an anti-aging molecule, followed by 200 milligrams of apigenin, a bioflavonoid compound that helps reduce anxiety and fight disease (chamomile extract, for example, is high in apigenin). Next comes 200 milligrams of green tea extract for additional disease prevention, and finally 100 milligrams of 98 percent pure trans-resveratrol. There are also 100 milligrams of green coffee bean for weight loss, healthy metabolism and improved heart health (however, this has 10 percent caffeine).

With its natural ingredient profile and energy-boosting benefits, Cymbiotika NMN has earned a spot on our list. This supplement comes in veggie capsule form—making it a great option for those who follow a plant-based diet—and is meant to be taken daily in two capsules. However, NMN supplementation is still being studied, and Baker recommends being aware of ongoing research. “More research is needed to determine the long-term safety and efficacy of NMN supplementation,” she says. Still, with an average 5/5-star rating on the Cymbiotika website, customers love this supplement. “I’m already feeling energy from taking this first thing in the morning,” writes a buyer named Nichole. “Loving how much sharper my brain feels now.”

If you're interested in this supplement brand, check out our Cymbiotika review. 

Pros:

• Natural ingredient profile
• Veggie capsules suitable for plant-based diets
• Contains energy-boosting properties
• 98 percent pure resveratrol

Cons:

• Costs more than $2 per day to take daily
• Not right for those who are sensitive to caffeine

Zhou Nutrition Resveratrol

Zhou

Key features & specs

• Resveratrol purity: 50 percent
• Resveratrol per dose: 1,000 milligrams
• Certifications: Non-GMO, cGMP and gluten-free
• Subscription: One to three months with 20% off every Subscribe & Save order
• Key ingredients: Resveratrol
• Sweeteners: None
• Best for: Heart health and antioxidant support
• Price per serving: $0.83

Unlike the first two supplements on our list, which include blends of active ingredients, Zhou Nutrition Resveratrol contains resveratrol only. As a supplement brand started by athletes and outdoor enthusiasts, Zhou Nutrition is a Utah-based company dedicated to whole-body wellness. This resveratrol supplement contains a high dose of 1,000 milligrams of 50 percent pure resveratrol derived from polygonum cuspidatum, or in simpler terms, Japanese knotweed.

While some customers may prefer a resveratrol-only supplement like the one offered by Zhou Nutrition, nutritionist and personal trainer Mary Sabat, MS, RDN, LD, says others might want a more well-rounded supplement. “It does not contain additional beneficial compounds like some other supplements,” she explains. Still, depending on your needs, this can be a pro or con.

We love this resveratrol supplement for its safety-first production, which includes non-GMO ingredients (or ingredients that haven’t been genetically modified) and a Current Good Manufacturing Practices or cGMP stamp. It’s also gluten-free and made in the U.S. Zhou Nutrition Resveratrol comes in veggie capsule form, and is meant to be taken daily in two capsules. Overall, this supplement has a 5/5-star rating on the Zhou Nutrition website. “I’ve tried other brands and they aren’t even in the same league,” writes a customer named Crystal. “I see my skin getting a more natural, healthy glow because of this product.”

Pros:

• Includes non-GMO ingredients
• Has Current Good Manufacturing Practices stamp
• No additional active ingredients
• Fair price point

Cons:

• Brand doesn’t disclose where lab testing is done
• Lower purity resveratrol

Garden of Life RAW Resveratrol

Garden of Life

Key features & specs

• Resveratrol purity: Undisclosed
• Resveratrol per dose: 350 milligrams
• Certifications: Non-GMO Project Verified, Certified Vegan, gluten-free, dairy-free and soy-free
• Subscription: One to six months with 5% off every Autoship & Save order
• Key ingredients: RAW resveratrol blend, RAW organic antioxidant blend and RAW probiotic and enzyme blend
• Sweeteners: None
• Best for: Heart health and healthy aging
• Price per serving: $0.70

Garden of Life RAW Resveratrol is a super-powered antioxidant formula designed to support heart health and healthy aging. As a Certified Vegan and mostly-organic supplement from the leading Garden of Life brand, which is one of the most reputable in its category, this product packs in as much trans-resveratrol as 200 bottles of red wine, Garden of Life promises. The biggest portion of the supplement includes a RAW resveratrol blend of 578 milligrams. This is made up of red wine (from cabernet sauvignon grape, to be exact) and fermented Japanese knotweed root. Within this resveratrol blend are 350 milligrams of active trans-resveratrol.

Making up a smaller portion of the supplement is 25 milligrams of a RAW organic antioxidant blend that includes a variety of organic fruits and veggies like apple, beet, broccoli, blueberry and green onion. There are also 16 milligrams of a RAW probiotic and enzyme blend that Sabat says promotes “digestive support” and can help regulate your gut health. This product is meant to be taken once daily as just one veggie capsule, which may be beneficial for those who have a tough time taking capsule or tablet supplements (as opposed to taking a larger two capsules).

With its natural resveratrol, antioxidant and probiotic blend, plus its certifications and lack of common allergens, we’ve deemed Garden of Life RAW Resveratrol worthy of a spot on our best resveratrol supplement guide. Customers agree as well. “After taking this for several months, my fingernails are now much stronger,” writes a 68-year-old customer named Bonnie. “There is an overall improvement in my skin. The skin on my hands and forearms looks 10 years younger.”

Related Post: Garden of Life Vitamins Review

Pros:

• Includes a blend of multiple resveratrol sources
• Packs in 25 milligrams of organic antioxidants
• Incorporates probiotics and enzymes for gut support
• No binders, fillers or carriers

Cons:

• Some people may not want probiotics in their supplement
• Higher dose of resveratrol

Life Extension Optimized Resveratrol Elite

Life Extension

Key features & specs

• Resveratrol purity: 18 percent
• Resveratrol per dose: 40 milligrams
• Certifications: Non-GMO Project Verified and gluten-free
• Subscription: One to six months with 5% off every Autoship & Save order
• Key ingredients: Nicotinamide riboside chloride, trans-resveratrol, galactomannans and Bio-Quercetin phytosome
• Sweeteners: None
• Best for: Fighting fatigue and anti-aging
• Price per serving: $0.56

Life Extension is a vitamin and supplement brand rooted in science, and their resveratrol supplement Life Extension Optimized Resveratrol Elite is as effective as the brand claims. “This supplement contains a combination of resveratrol and quercetin, another polyphenol with antioxidant and anti-inflammatory effects,” Baker says. Quercetin helps fight age-related diseases, giving customers extra protection when paired with resveratrol. A resveratrol blend accounts for 55 milligrams of this supplement (with 40 milligrams coming from Japanese knotweed), while heart-healthy nicotinamide riboside makes up the majority at 300 milligrams.

If you’re looking for a high dose of resveratrol, this product isn’t it, but those seeking out a product with multiple benefits as they relate to aging and energy should keep this gluten-free and vegan supplement at the top of their list. It comes in vegetarian capsule form, and is meant to be taken once daily as one capsule. Customers have mostly positive reviews, with one buyer noting that their “strength is improving” along with their stamina, but another claims that they've had trouble sleeping because the extra energy it provides “lingers on” at night.

Pros:

• Includes quercetin to fight age-related disease
• Designed to combat fatigue
• Gluten-free and vegan

Cons:

• Very low purity resveratrol and dose
• Some customers report trouble sleeping

MRM Nutrition Resveratrol

MRM Nutrition

Key features & specs

• Resveratrol purity: Undisclosed
• Resveratrol per dose: 100 milligrams
• Certifications: Non-GMO Project Verified, gluten-free and vegan
• Subscription: One to six months with 5% off every Autoship & Save order
• Key ingredients: Asian knotweed root extract, red wine extract and grape seed extract
• Sweeteners: None
• Best for: Brain support and healthy aging
• Price per serving: $0.21

MRM Nutrition Resveratrol is another supplement on our list that contains resveratrol only as its active ingredient. MRM Nutrition, a supplement brand founded by professional nutritionists, clinical researchers and natural food specialists, specializes in holistic products. That’s why their resveratrol supplement pulls resveratrol from three natural sources that include Asian knotweed root extract, red wine extract and grape seed extract. Altogether, there are 100 milligrams of resveratrol per serving, making this supplement a moderate choice in terms of potency.

Another perk that makes this supplement one of our favorites: it costs just $0.21 per serving. “MRM Nutrition Resveratrol may be a good option for individuals looking for a simple and affordable resveratrol supplement that also contains grape seed extract, which may have antioxidant and anti-inflammatory effects,” Baker explains. Grape seed extract has the power to fight inflammation, cardiovascular disease, hypertension, diabetes and more. This supplement comes in vegan capsule form, and is meant to be taken as one capsule once daily. Customers praise the small size of the capsule (meaning it’s easy to swallow), with one buyer noting that there’s “no taste” and that they’ve noticed “less wrinkles” on their skin.

Pros:

• Budget-friendly price point
• Three sources of resveratrol
• Small capsules are easy to take

Cons:

• Resveratrol purity isn’t disclosed

NOW Foods Resveratrol

NOW Foods

Key features & specs

• Resveratrol purity: Undisclosed
• Resveratrol per dose: 200 milligrams
• Certifications: cGMP Certified, UL Certified (third-party tested by Underwriter Laboratories), gluten-free, dairy-free, soy-free, nut-free, egg-free, halal and vegan
• Subscription: One to six months with 5% percent off every Autoship & Save order
• Key ingredients: Japanese knotweed and alcohol-free red wine extract
• Sweeteners: None
• Best for: Cardiovascular support and fighting inflammation
• Price per serving: $0.17

NOW Foods is a leading supplement brand that produces a wide variety of products for different needs at fair price points. NOW Foods Resveratrol, for example, costs just $0.17 per serving and packs in 200 milligrams of resveratrol in each dose. It contains a blend of 400 milligrams of Japanese knotweed and 10 milligrams of alcohol-free red wine extract, which may be beneficial for those looking for red wine benefits without the alcohol. While this dose of red wine extract is relatively low, Baker says it’s “important to note that high doses of red wine extract may cause gastrointestinal discomfort.” However, you probably won’t need to worry about that with this product.

With its budget-friendly price point and resveratrol-loaded blend, NOW Foods Resveratrol is worthy of a spot on our list, and is a great choice for cardiovascular support and fighting inflammation without breaking the bank. It comes in veggie capsule form, and is meant to be taken once daily as one capsule. “I’ve been taking resveratrol for a few months now and my skin and hair has improved significantly,” one customer writes in a review. “It’s all the good stuff in red wine concentrated into a pill form.”

Pros:

• Third-party tested and certified
• Free from major allergens (gluten, nuts, soy, egg and dairy)
• Uses alcohol-free red wine extract
• Low price point per serving

Cons:

• Resveratrol purity is undisclosed
• Some customers report smelly capsules

What Is Resveratrol?

Resveratrol is a polyphenol, a type of powerful antioxidant found in natural plant sources like berries and nuts, that can improve cardiovascular health and overall wellness. It can also be found in high concentrations of red wine. However, supplement forms of resveratrol are much more potent and deliver a higher dose of resveratrol than you’ll get from eating food sources. “It may be difficult to obtain therapeutic doses of resveratrol through diet alone,” Baker says.

Resveratrol dietary supplements are typically sourced from Japanese knotweed, a traditional Japanese herbal remedy that has long been used for pain relief. Japanese knotweed includes trans-resveratrol, the source of resveratrol that’s easiest for your body to digest. While most resveratrol supplements include this active ingredient, they can widely differ in purity, dose and quality. Resveratrol nutritional supplements also come in various forms such as capsules, tablets and liquid. While some supplements contain resveratrol alone, others combine resveratrol with anti-aging compounds like nicotinamide mononucleotide, Baker explains.

Benefits of Resveratrol

Resveratrol benefits are wide-ranging and encompass everything from slowing cognitive decline to preventing skin aging. Here’s everything there is to know about the effects of resveratrol.

Anti-aging

One of the most popular uses of resveratrol supplements is for their anti-aging benefits. Studies show that resveratrol may not only prevent skin aging but can also protect against the signs of aging that aren’t always visible, such as age-related diseases. This powerful healthy aging and anti-aging supplement can actually increase lifespan by activating genes involved in longevity and cellular repair, Sabat says, like the SirT1 sirtuins gene.

Brain health

Research has found that resveratrol does wonders for your brain health. Resveratrol, an NAD+ booster, can improve memory issues from sleep deprivation, boost cognitive function and even promote positive changes in behavior (NAD+ influences cell function). This brain-enhancing supplement is also used to prevent Alzheimer’s disease or slow down cognitive decline as an adjunct treatment for diagnosed neurodegenerative diseases.

Blood sugar

Some people with diabetes use resveratrol supplements as part of their care management plan alongside a diabetes-friendly diet. The reason? Resveratrol has the power to keep blood glucose levels in check, increase insulin sensitivity and fight chronic inflammation associated with diabetes, according to early data. While research in this area is still ongoing, resveratrol is steadily becoming a promising supplement for diabetes care and management.

Cancer treatment

One of the most impactful and powerful benefits that resveratrol supplementation may offer is its support for cancer treatment. “Resveratrol has been shown to have anti-cancer properties, particularly in preventing the growth and spread of certain types of cancer cells,” Sabat says. According to research, resveratrol can actually induce cell death or eliminate cancer cells by changing their proteins, which helps slow the process of these cells dividing and multiplying.

Heart health

Another popular use for resveratrol is for its many heart-healthy benefits. Resveratrol can “reduce blood pressure, lower LDL (or “bad”) cholesterol and reduce the risk of blood clots,” Sabat explains. Studies have found that resveratrol can also improve cardiac structure, lessen stress on your heart walls, increase blood flow, prevent damage to blood vessels and improve overall heart functioning, all of which can help fight heart disease.

Inflammation

As a potent anti-inflammatory supplement, many people turn to resveratrol to reduce inflammation. Studies show that resveratrol can significantly lower inflammation factors and malondialdehyde levels, which is a marker of oxidative stress, or an imbalance in the body between free radicals and antioxidants. Resveratrol helps the body detoxify and repair cell and tissue damage. Other popular anti-inflammatory supplements are turmeric, ashwagandha and vitamin A.

Resveratrol Precautions

Like with all supplements, there are important precautions to take before starting or considering resveratrol. While resveratrol side effects are little-to-none, higher doses of 2.5 grams or more per day could cause gastrointestinal discomfort such as nausea, vomiting and diarrhea. Those with non-alcoholic fatty liver disease might also want to steer clear of resveratrol supplements since they can cause liver dysfunction within this particular group.

While resveratrol is generally considered safe, Baker suggests being cautious if you take any prescription medication. “Resveratrol may interact with certain medications, such as blood thinners, and may affect how the body metabolizes some drugs,” she says. Therefore, if you’re taking medication or have a medical condition, be sure to speak to a healthcare professional about the benefits and risks of taking a resveratrol supplement. It’s also important to keep in mind that as a dietary supplement, resveratrol isn’t approved or regulated by the FDA.

How to Choose the Best Resveratrol for You

Resveratrol supplement brands vastly differ in the types of products that they offer. Consider these factors as you shop for the right resveratrol supplement for your needs and budget.

Purity

Resveratrol supplements typically come in three types of purities: organic root extract, 50 percent standardized and 98 percent standardized (although these numbers can vary). Since organic root extract is crushed and put into capsules, the purity is unknown and can vary depending on the health and quality of the plant, in addition to the condition it’s grown in. Standardized purities contain that much amount of resveratrol (such as 50 percent). More pure resveratrol supplements will always be your best bet, since this helps ensure products will be free of harmful substances like bacteria or heavy metals that can be dangerous to your health.

Dose

More isn’t always better, and the same is true for resveratrol. “The optimal dosage of resveratrol is not yet known,” Sabat explains. Instead, most resveratrol supplements come in a dose of 500 to 1,000 milligrams. Keep in mind, however, that a greater dose may increase your risk of upset stomach or discomfort. If you have a sensitive stomach, it’s a good idea to start with a low dose of resveratrol and slowly work your way up to your desired dose level, or stay at a low dose.

Quality

“Not all resveratrol supplements are created equal, and some may not contain the amount of resveratrol listed on the label,” Sabat cautions. Therefore, high-quality resveratrol supplements undergo additional testing to ensure their safety and effectiveness. Sabat recommends looking for a product that has been third-party tested for purity and potency; this means that the supplement has been independently tested by an organization that wasn’t involved in its production.

Form

You can find resveratrol supplements in several forms, such as capsules, tablets, powder and liquid. As for the best form, Sabat says there’s no “one-size-fits-all” answer. Instead, consider your preferences. Do you have a tough time swallowing pills? Does the idea of using a powder supplement sound like a mess? Do you follow a vegetarian or vegan diet and prefer vegetarian capsules? Be sure to find a product that will be easy and comfortable for you to take.

Price

Supplements can get pricey, so it’s important to set a budget for a resveratrol supplement, especially if you plan on taking it daily and will need to refresh your supply every one or two months. Depending on the brand and purity, you can buy resveratrol supplements for as low as $0.20 per serving to as high as $2 per serving or more. More pure resveratrol supplements will naturally be more expensive, but may be worth it for the safety and efficacy benefits.

How We Chose the Best Resveratrol

While there are many resveratrol supplements on the market, some are simply better than others—and here’s how we prioritized which supplements deserved a spot on our list. In making our decisions, we considered efficacy, dosage, brand reputation, product quality and price. We also considered customer reviews, third-party testing, certifications and subscription options.

Resveratrol FAQs

Which form of resveratrol is best?

Resveratrol supplements come in different forms that include capsules, tablets, powder and liquid. While no one form is better than the other, you may prefer liquid or powder to capsules or tablets, for example, if you have a hard time taking pills.

Should I take resveratrol in the morning or at night?

Depending on who you ask or where you look, you’ll find very different recommendations for the best time to take resveratrol. You may want to try taking resveratrol in the morning and night on separate days to see which option works better for you, but be sure to take resveratrol with food to help increase absorption (or bioavailability) of the supplement and decrease side effect risk.

What is trans-resveratrol?

Trans-resveratrol is the source of resveratrol that’s easiest for your body to digest. Resveratrol comes in two forms: trans-resveratrol and cis-resveratrol, the latter of which isn’t as effective.

Does resveratrol actually work?

As one of the most studied bioactive compounds in food, research backs up the many health benefits of resveratrol. As for whether or not it will work for you will depend on your reason for taking resveratrol supplements, your metabolism and the overall quality of the product you buy.

Can you get resveratrol naturally?

You can get resveratrol naturally through plant sources like berries and nuts, or by drinking red wine or the juices of these fruits. However, the amount of resveratrol in these sources is “relatively low,” Baker says. “Red wine is often touted as a source of resveratrol, but it should be consumed in moderation due to the potential negative effects of alcohol consumption.” Plus, red wine can pack on calories, while resveratrol supplements are a low-calorie alternative.

Does resveratrol cause weight gain?

Resveratrol shouldn’t cause weight gain. In fact, it can do quite the opposite and help you lose weight and reduce your body mass index when paired with a healthy diet and exercise.

Takeaway: Are Resveratrol Supplements Worth It?

Whether you’re considering resveratrol supplements for their many health benefits or anti-aging properties, study after study consistently backs up the pros of taking these products. Still, it’s important to remember that resveratrol supplements aren’t for everyone, and it’s smart to check with a healthcare provider before starting resveratrol if you take medication or have a medical condition.

Prices are accurate and items in stock as of publish time.