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#14 LSU vs. Mississippi State Prediction, CFB Picks & Odds: Sat, 9/16

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After having to take on a top-five team in the Florida State Seminoles to open the season, the LSU Tigers were able to bounce back in a big way this past weekend with their huge win over a different Tigers team - Grambling State. Now, it’s time to start facing fellow SEC teams, as they head over to take on the Mississippi State Bulldogs.

We’ve shared our best LSU vs. Mississippi State prediction Saturday afternoon’s game, which pairs perfectly with a ‘Bet $5, get $200’ DraftKings Sportsbook new-user promo.

LSU VS. MISSISSIPPI STATE PREDICTION: Under 54.5 Points (-110 at DraftKings Sportsbook)

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LSU Tigers vs. Mississippi State Bulldogs Prediction: CFB This Week

LSU’s schedule is already tough enough being in the SEC West, so starting their season with Florida State was certainly not the friendliest way to do so. However, they were able to get their confidence boosting win at home this past weekend.

Firstly, we’re predicting another Tigers victory, likely of around a touchdown. With the point spread approaching double-digits, we’d rather not get burned by a last second field goal by the Bulldogs for a backdoor cover. Instead, we’re focusing on the total, or over/under, with our best LSU vs. Mississippi State prediction.

LSU vs. Mississippi State Picks & CFB Best Bets for Saturday Including Under 54.5 Points

The Tigers have won each of their last two contests against the Bulldogs, and with QB Jayden Daniels having experience in this matchup, we fully expect them to continue that trend. Similarly, that trend goes back even further - they’ve won seven of their last 10 games against Mississippi State.

However, they’re 5-5 in terms of against the spread, so again, we’d rather not target that betting market. A different trend we can back is the fact that this matchup has stayed under the total in seven of the last 10 meetings. Of course, the most recent are the most important, as turnover in college football is a key aspect of making predictions.

Last season, there were 47 points scored, and the year prior, there were 53 points scored in LSU’s close 28-25 victory. Despite the Tigers’ 72 points this past weekend, they’ll be facing an SEC defense, not Grambling State. Mississippi State has started 2-0 by holding opponents to just 31 points across the first two weeks.

Bulldogs QB Will Rogers is also not on nearly as impressive of a pace as last season with just 389 passing yards on the year this far. They’ll likely want to slow the game down a bit, as will LSU being in one of the most difficult road environments in the country. With all that said, our best LSU vs. Mississippi State prediction is on Under 54.5 points (-110 at DraftKings Sportsbook).

How to Bet $5 on Under 54.5 at DraftKings Sportsbook & Get $200 No Matter the Result

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Latest LSU vs. Mississippi State Betting Lines, Odds & Spread for 9/16 via DraftKings

When it comes to our LSU vs. Mississippi State prediction on under 54.5 points, that has -110 odds at DraftKings Sportsbook, so an $11 wager profits $10 as long the game ends with 54 or fewer points scored. You can also see each of the standard markets below:

Point Spread:

  • LSU Tigers -9 (-110) vs. Mississippi State Bulldogs +9 (-110)

Money Line:

  • LSU Tigers (-360) vs. Mississippi State Bulldogs (+285)

Game Total (Over/Under)

  • Over 54.5 (-110) vs. Under 54.5 (-110)

Grambling St. vs. LSU Score Last Week

As mentioned while breaking down our LSU vs. Mississippi State prediction, LSU was able to bounce back in a big way this past weekend, which you can see with the final score below:

  • Grambling State Tigers 10 vs. LSU Tigers 72

We certainly aren’t expecting another 72-point performance this Saturday, so be sure to take advantage of our LSU vs. Mississippi State prediction by signing up for a NEW account at DraftKings for your $200 worth of bonus bets guaranteed.

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