Colts vs. Bills Picks & Odds + BetMGM $1,000 Bonus: NFL Preseason W1

The Buffalo Bills are set to clash with the Indianapolis Colts in a preseason showdown this Saturday. Last season, the Bills showcased stellar performance, recording a 13-3 run and securing the second seed in the AFC East. Their domination was evident as they clinched the division, finishing four games ahead of Miami, especially after a triumphant end to the season with seven consecutive victories. Their home game record was impressive as well, with a 7-1 streak.

On the other hand, it was a challenging season for the Indianapolis Colts, ending with a 4-12-1 record and a seven-game losing streak. They only managed to outpace Houston in the AFC South standings. Let's delve into some top picks for the Colts vs Bills matchup. You can also check out one of our favorite offers better known as the BetMGM $1,000 bonus for your Colts vs. Bills picks by signing up for a new account with this link.

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Colts vs. Bills Expert Pick: Bills +3.5 (-110 at BetMGM)

Last year saw the trio of Matt Ryan, Sam Ehlinger and Nick Foles managing a mere 17 touchdowns against 20 interceptions - a disheartening statistic for Colts enthusiasts. Michael Pittman remains the receiver to watch, with quarterbacks eyeing him as their main playmaker. Other potential stars include Alec Pierce, Isaiah McKenzie, Ashton Dulin and Breshard Perriman. A diverse lineup is anticipated for their first preseason game.

Though Allen is set to sit this game out, Buffalo will evaluate backups Kyle Allen and Matt Barkley. James Cook is poised as the probable starting running back, with players like Damien Harris, Latavius Murray and Darrynton Evans awaiting their turn.

Even though it's just the preseason, it's unexpected to see the Colts favored by such a margin. This matchup promises to be tighter than anticipated. Even with the Bills fielding their backups, they'll be showcasing a skilled lineup on the field. For our Colts vs. Bills picks, we’re taking the Bills +3.5 (-110 at BetMGM Sportsbook). This presents the perfect opportunity to nab the BetMGM $1,000 bonus.

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