Whisenhunt announced the injury Monday.
The coach says the Titans will know more Tuesday and that he couldn't comment much more until the team has more information. But he says the only question is how much time Brown, 6-foot-1 and 248 pounds, will miss this season.
The 24-year-old Brown started and was hurt early in the Titans' 26-10 win at Kansas City. Whisenhunt says the linebacker was trying to tackle when his hand got caught in a shoulder pad with his feet coming out.
Zaviar Gooden replaced Brown in the game.
AP NFL website: www.pro32.ap.org and www.twitter.com/AP-NFL