The 49ers are 2-Point Favorites to Beat the Bills in Week 13

It will be extremely cold. It might even snow. These conditions favor the Bills. In addition, the 49ers will play the previous week in Green Bay, which means they'll have two cold road games in a row.
Buffalo Bills quarterback Josh Allen (17) steps into this throw over the middle. Allen only threw
Buffalo Bills quarterback Josh Allen (17) steps into this throw over the middle. Allen only threw / Jamie Germano/Rochester Democrat and
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One of the toughest opponents on the 49ers' schedule for 2024 is the Buffalo Bills.

The 49ers have faced Bill quarterback Josh Allen just once, and he beat them 34-24. Also threw for 375 yards and 4 touchdowns and posted a quarterback rating of 139.1. Of course, this was 2020 and the 49ers are much better now than they were back then.

That's why the 49ers are two-point favorites to beat the Bills on the road in Week 13. The 49ers are one of the best teams in the NFL, while the Bills are reloading after trading no. 1 wide receiver Stefon Diggs.

Beat teams have beaten the 49ers without a true no. 1 wide receiver in the past. The Ravens beat the 49ers last season with rookie Zay Flowers as their no. 1 wide receiver, and the Chiefs beat the 49ers in the Super Bowl with rookie Rashee Rice as their no. 1 wide receiver.

The Chiefs and the Ravens have something else in common -- excellent tight ends and elite quarterbacks who are tough to contain inside the pocket. If the 49ers have a tough time defending Lamar Jackson, how will they do against Allen, who's a bigger, more powerful runner than Jackson?

Another tough aspect of this game for the 49ers is the weather -- it will be extremely cold. It might even snow. These conditions favor the Bills. In addition, the 49ers will play the previous week in Green Bay, which means they'll have two cold road games in a row.

I wouldn't bet on the 49ers to win this one.


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Grant Cohn

GRANT COHN

Grant Cohn has covered the San Francisco 49ers daily since 2011. He spent the first nine years of his career with the Santa Rosa Press Democrat where he wrote the Inside the 49ers blog and covered famous coaches and athletes such as Jim Harbaugh, Colin Kaepernick and Patrick Willis. In 2012, Inside the 49ers won Sports Blog of the Year from the Peninsula Press Club. In 2020, Cohn joined FanNation and began writing All49ers. In addition, he created a YouTube channel which has become the go-to place on YouTube to consume 49ers content. Cohn's channel typically generates roughly 3.5 million viewers per month, while the 49ers' official YouTube channel generates roughly 1.5 million viewers per month. Cohn live streams almost every day and posts videos hourly during the football season. Cohn is committed to asking the questions that 49ers fans want answered, and providing the most honest and interactive coverage in the country. His loyalty is to the reader and the viewer, not the team or any player or coach. Cohn is a new-age multimedia journalist with an old-school mentality, because his father is Lowell Cohn, the legendary sports columnist for the San Francisco Chronicle from 1979 to 1993. The two have a live podcast every Tuesday. Grant Cohn grew up in Oakland and studied English Literature at UCLA from 2006 to 2010. He currently lives in Oakland with his wife.