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Colts defensive tackle DeForest Buckner is set to return to the lineup on Monday night.

Colts Receive Good News on DT DeForest Buckner Ahead of Monday’s Game vs. Niners

Mike McDaniel

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5 Minutes Ago

Eric Saubert

Seahawks Week 16 rooting guide: is clinching NFC No. 1 seed on the table?

Richie Whitt

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37 Minutes Ago

Nov 30, 2025; Cleveland, Ohio, USA; Cleveland Browns running back Dylan Sampson (22) runs the ball during the second half against the San Francisco 49ers at Huntington Bank Field. Mandatory Credit: Ken Blaze-Imagn Images

What the Biggest Challenge Will be for the 49ers Against Indianapolis

Jose Sanchez

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37 Minutes Ago

Nov 16, 2025; Glendale, Arizona, USA; San Francisco 49ers defensive coordinator Robert Saleh speaks with 49ers safety Malik Mustapha (6) in the third quarter against the Arizona Cardinals at State Farm Stadium. Mandatory Credit: Matt Kartozian-Imagn Images

One 49ers Player is Garnering Heavy Praise From Robert Saleh

Jose Sanchez

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3 Hours Ago

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Injuries

Nov 16, 2025; Glendale, Arizona, USA; San Francisco 49ers general manager John Lynch speaks on the sidelines before the game against the Arizona Cardinals at State Farm Stadium. Mandatory Credit: Matt Kartozian-Imagn Images

John Lynch Dismisses “Injury-Prone” Label for This 49ers Player

Henry Cheal

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18 Hours Ago

Sep 29, 2024; Santa Clara, California, USA; San Francisco 49ers wide receiver Brandon Aiyuk (11) warms up before the game against the New England Patriots at Levi's Stadium. Mandatory Credit: Sergio Estrada-Imagn Images

This Is the Most Honest Take on the 49ers-Brandon Aiyuk Situation

Henry Cheal

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20 Hours Ago

5 49ers who need to step up to beat the Colts

Parker Hurley

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21 Hours Ago

Dec 14, 2025; Seattle, Washington, USA; Indianapolis Colts quarterback Philip Rivers (17) walks to the huddle during the first quarter against the Seattle Seahawks at Lumen Field. Mandatory Credit: Kevin Ng-Imagn Images

Colts' Limited Offense Reveals Clear Betting Value vs. 49ers

Michael Greene

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23 Hours Ago

3 ways the San Francisco 49ers can expose the Indianapolis Colts

Parker Hurley

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23 Hours Ago

Oct 2, 2025; Inglewood, California, USA; San Francisco 49ers head coach Kyle Shanahan during the second half at SoFi Stadium. Mandatory Credit: Kirby Lee-Imagn Images

Kyle Shanahan Sounds Off on the Colts’ Run Game

Jose Sanchez

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Dec 19, 2025

Dec 14, 2025; New Orleans, Louisiana, USA; New Orleans Saints quarterback Tyler Shough (6) throws the ball during the second quarter against the Carolina Panthers at Caesars Superdome. Mandatory Credit: Matthew Hinton-Imagn Images

NFL Week 16 Survival Pool Strategy: Saints, Texans and 3 More Winning Picks

Michael Rovetto

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Dec 19, 2025

4 Indianapolis Colts that the San Francisco 49ers must focus on

Parker Hurley

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Dec 19, 2025

Nov 24, 2025; Santa Clara, California, USA; San Francisco 49ers head coach Kyle Shanahan walk off the field after defeating the Carolina Panthers at Levi's Stadium. Mandatory Credit: Kelley L Cox-Imagn Images

One 49ers player is almost guaranteed to get a $500k bonus vs. Colts

Henry Cheal

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Dec 19, 2025

Jordan Love led the Packers to a 28–21 win over the Bears two weeks ago.

Key Matchups, Predictions for Packers-Bears and More NFL Week 16 Games

Matt Verderame

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Dec 19, 2025

The 49ers absolutely nailed this contract decision

Parker Hurley

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Dec 18, 2025

Nov 9, 2025; Miami Gardens, Florida, USA; Miami Dolphins outside linebacker Matthew Judon (8) runs on the field before a game against the Buffalo Bills at Hard Rock Stadium. Mandatory Credit: Jeff Romance-Imagn Images

Why the 49ers Must Avoid Adding Former Dolphin Matthew Judon

Jose Sanchez

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Dec 18, 2025

The 49ers' drama with Brandon Aiyuk takes another bizarre turn

Grant Cohn

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Dec 18, 2025

Dec 14, 2025; Santa Clara, California, USA; San Francisco 49ers wide receiver Jauan Jennings (15) enters the field prior to the first half against the Tennessee Titans at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

Fantasy Football Week 16 WR/CB Matchups: Jauan Jennings Rises, George Pickens Falls

Thomas Carelli

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Dec 18, 2025

Dec 14, 2025; Santa Clara, California, USA; San Francisco 49ers wide receiver Ricky Pearsall (1) stiff arms Tennessee Titans cornerback Marcus Harris (26) during the third quarter at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

Four 49ers Pop up on First Injury Report for Week 16

Jose Sanchez

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Dec 18, 2025

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